Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 20/20 | 0.55 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.54 |
| ▸ | PDE2A | O00408 | 1/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.52 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.52 |
| ▸ | PDE6D | O43924 | 1/20 | 0.52 |
| ▸ | PDE8A | O60658 | 1/20 | 0.52 |
| ▸ | PDE9A | O76083 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | PDE6A | P16499 | 1/20 | 0.52 |
| ▸ | PDE6G | P18545 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | PDE6B | P35913 | 1/20 | 0.52 |
| ▸ | PDE6C | P51160 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29707547 | 0.95 | PDE5A (0.58) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL29904531 | 0.95 | PDE5A (0.58) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL5452865 | 0.89 | PDE5A (0.62) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL5452873 | 0.89 | PDE5A (0.62) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL30848723 | 0.88 | PDE5A (0.67) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL18073972 | 0.87 | PDE5A (0.60) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL28891471 | 0.86 | PDE5A (0.73) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL5450704 | 0.83 | PDE5A (0.54) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL5450699 | 0.83 | PDE5A (0.54) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL5450729 | 0.83 | PDE5A (0.66) | PDE5APDE3BPDE3APDE2AABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115598338-A | Colloidal gold test strip for detecting PDE-5 inhibitor and preparation method and application thereof | 广东省药品检验所（广东省药品质量研究所、广东省口岸药品检验所）（CN） | 2023-01-13 | — | — | CN | disclosed |