Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 18/20 | 0.58 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.58 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.58 |
| ▸ | PDE2A | O00408 | 1/20 | 0.58 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.58 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.58 |
| ▸ | PDE6D | O43924 | 1/20 | 0.58 |
| ▸ | PDE8A | O60658 | 1/20 | 0.58 |
| ▸ | PDE9A | O76083 | 1/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | PDE6A | P16499 | 1/20 | 0.58 |
| ▸ | PDE6G | P18545 | 1/20 | 0.58 |
| ▸ | PDE4A | P27815 | 1/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | PDE6B | P35913 | 1/20 | 0.58 |
| ▸ | PDE6C | P51160 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29904531 | 1.00 | PDE5A (0.58) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL30199879 | 0.95 | PDE5A (0.55) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL18073972 | 0.92 | PDE5A (0.60) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL5450729 | 0.88 | PDE5A (0.66) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL5450733 | 0.88 | PDE5A (0.66) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL30199978 | 0.88 | PDE5A (0.74) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL30199894 | 0.87 | PDE5A (0.75) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL6497382 | 0.86 | PDE5A (0.79) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL6497379 | 0.86 | PDE5A (0.79) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL30434848 | 0.86 | PDE5A (0.79) | PDE5APDE3BPDE3APDE2AABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240115678-A1 | PERSONALIZED MULTIDISCIPLINARY CANCER THERAPY | VELTMEYER JAMES (US) | 2024-04-11 | — | — | US | claimed |
| US-11903992-B2 | Composition comprising lidocaine, l-carnosine and dexpanthenol | CELLIX BIO PRIVATE LIMITED (IN) | 2024-02-20 | — | — | US | claimed |
| WO-2024026505-A2 | DISRUPTION OF TELOCYTE ACTIVITY | PATEL AMIT (US) | 2024-02-01 | — | — | WO | claimed |
| US-20220401541-A1 | INTRATUMORAL ADMINISTRATION OF IMMUNE CELLULAR THERAPEUTICS | FIBROBIOLOGICS, INC. | 2022-12-22 | — | — | US | claimed |
| WO-2022190030-A1 | A TOPICAL FORMULATION FOR THE TREATMENT OF SKIN DISEASES | AVACA PHARMA PRIVATE LIMITED (IN) | 2022-09-15 | — | — | WO | claimed |
| EP-4051305-A1 | INTRATUMORAL ADMINISTRATION OF IMMUNE CELLULAR THERAPEUTICS | Figene, LLC (US) | 2022-09-07 | — | — | EP | claimed |
| US-20220233629-A1 | COMPOSITION COMPRISING LIDOCAINE, L-CARNOSINE AND DEXPANTHENOL | CELLIX BIO PRIVATE LIMITED (IN) | 2022-07-28 | — | — | US | claimed |
| WO-2022157587-A1 | A COMPOSITION COMPRISING LIDOCAINE, L-CARNOSINE AND DEXPANTHENOL | CELLIX BIO PRIVATE LIMITED (IN) | 2022-07-28 | — | — | WO | claimed |
| US-20220184052-A1 | COMPOSITION COMPRISING FEXOFENADINE | CELLIX BIO PRIVATE LIMITED (IN) | 2022-06-16 | — | — | US | claimed |
| US-20250025444-A1 | TREATMENT OF NEURODEGENERATIVE DISEASES VIA ADMINISTRATION OF BUNTANETAP AND A PHOSPHODIESTERASE INHIBITOR | ANNOVIS BIO, INC. (US) | 2025-01-23 | — | — | US | disclosed |
| US-20240382511-A1 | NICOTINAMIDE MONONUCLEOTIDE DERIVATIVES AND USE THEREOF FOR THE TREATMENT OF HEART FAILURE WITH PRESERVED EJECTION FRACTION | NUVAMID SA (CH) | 2024-11-21 | — | — | US | disclosed |
| CN-113271949-B | Sildenafil for the treatment of osteoarthritis | 阿尔特罗亚公司 | 2024-09-27 | — | — | CN | disclosed |
| EP-4355335-A1 | NICOTINAMIDE MONONUCLEOTIDE DERIVATIVES AND USE THEREOF FOR THE TREATMENT OF HEART FAILURE WITH PRESERVED EJECTION FRACTION | Nuvamid SA (CH) | 2024-04-24 | — | — | EP | disclosed |
| US-20240115678-A1 | PERSONALIZED MULTIDISCIPLINARY CANCER THERAPY | VELTMEYER JAMES (US) | 2024-04-11 | — | — | US | disclosed |
| WO-2022190030-A1 | A TOPICAL FORMULATION FOR THE TREATMENT OF SKIN DISEASES | AVACA PHARMA PRIVATE LIMITED (IN) | 2022-09-15 | — | — | WO | disclosed |
| EP-4051305-A1 | INTRATUMORAL ADMINISTRATION OF IMMUNE CELLULAR THERAPEUTICS | Figene, LLC (US) | 2022-09-07 | — | — | EP | disclosed |
| WO-2022175829-A1 | TOPICAL FORMULATIONS AND COMPOSITIONS | CELLIX BIO PRIVATE LIMITED (IN) | 2022-08-25 | — | — | WO | disclosed |
| WO-2022157587-A1 | A COMPOSITION COMPRISING LIDOCAINE, L-CARNOSINE AND DEXPANTHENOL | CELLIX BIO PRIVATE LIMITED (IN) | 2022-07-28 | — | — | WO | disclosed |
| US-20220233629-A1 | COMPOSITION COMPRISING LIDOCAINE, L-CARNOSINE AND DEXPANTHENOL | CELLIX BIO PRIVATE LIMITED (IN) | 2022-07-28 | — | — | US | disclosed |
| US-20220184052-A1 | COMPOSITION COMPRISING FEXOFENADINE | CELLIX BIO PRIVATE LIMITED (IN) | 2022-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240382511-A1 | NICOTINAMIDE MONONUCLEOTIDE DERIVATIVES AND USE THEREOF FOR THE TREATMENT OF HEART FAILURE WITH PRESERVED EJECTION FRACTION | NNT, NAMPT, SIRT3 | PDE5A 294/4885PDE3B 230/4885PDE3A 214/4885 |
| US-11903992-B2 | Composition comprising lidocaine, l-carnosine and dexpanthenol | VNN1, LPL, HMGB1 | PDE5A 418/4885PDE3B 837/4885PDE3A 296/4885 |
| US-20250025444-A1 | TREATMENT OF NEURODEGENERATIVE DISEASES VIA ADMINISTRATION OF BUNTANETAP AND A PHOSPHODIESTERASE INHIBITOR | PDE5A, PDE3A, PDE2A | PDE5A 1/4885PDE3B 4/4885PDE3A 2/4885 |
| US-20220233629-A1 | COMPOSITION COMPRISING LIDOCAINE, L-CARNOSINE AND DEXPANTHENOL | VNN1, LPL, HMGB1 | PDE5A 418/4885PDE3B 837/4885PDE3A 296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.