Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 20/20 | 0.67 |
| ▸ | PDE6C | P51160 | 2/20 | 0.66 |
| ▸ | PDE11A | Q9HCR9 | 2/20 | 0.66 |
| ▸ | PDE2A | O00408 | 1/20 | 0.66 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.66 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.66 |
| ▸ | PDE6D | O43924 | 1/20 | 0.66 |
| ▸ | PDE8A | O60658 | 1/20 | 0.66 |
| ▸ | PDE9A | O76083 | 1/20 | 0.66 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | HTR1A | P08908 | 1/20 | 0.66 |
| ▸ | PDE6A | P16499 | 1/20 | 0.66 |
| ▸ | PDE6G | P18545 | 1/20 | 0.66 |
| ▸ | PDE4A | P27815 | 1/20 | 0.66 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.66 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.66 |
| ▸ | PDE6B | P35913 | 1/20 | 0.66 |
| ▸ | PDE1A | P54750 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30199978 | 0.94 | PDE5A (0.74) | PDE5APDE6CPDE11APDE2AABCC4 | |
| SCHEMBL30199879 | 0.88 | PDE5A (0.55) | PDE5APDE6CPDE11APDE2AABCC4 | |
| SCHEMBL30199894 | 0.88 | PDE5A (0.75) | PDE5APDE6CPDE11APDE2AABCC4 | |
| SCHEMBL6716951 | 0.88 | PDE5A (0.75) | PDE5APDE6CPDE11APDE2AABCC4 | |
| Sildenafil SCHEMBL492566 | 0.86 | PDE5A (0.77) | PDE5APDE6CPDE11APDE2AABCC4 | |
| SCHEMBL29282029 | 0.86 | PDE5A (0.76) | PDE5APDE6CPDE11APDE2AABCC4 | |
| SCHEMBL28417921 | 0.85 | PDE5A (0.89) | PDE5APDE6CPDE11APDE2AABCC4 | |
| SCHEMBL6715447 | 0.84 | PDE5A (0.74) | PDE5APDE6CPDE11APDE2AABCC4 | |
| SCHEMBL18912667 | 0.83 | PDE5A (0.65) | PDE5APDE6CPDE11APDE2AABCC4 | |
| SCHEMBL29904531 | 0.83 | PDE5A (0.58) | PDE5APDE6CPDE11APDE2AABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117969703-A | Method for detecting content of thionafil derivative in food or Chinese patent medicine | 上海市食品药品检验研究院 | 2024-05-03 | — | — | CN | claimed |
| CN-117890459-A | Quick screening method for illegally adding chemical drugs into foods based on MSRIT-MS/MS | 南京市食品药品监督检验院 | 2024-04-16 | — | — | CN | claimed |
| CN-117890459-B | Quick screening method for illegally adding chemical drugs into foods based on MSRIT-MS/MS | 南京市食品药品监督检验院 | 2024-10-18 | — | — | CN | disclosed |
| CN-117969703-A | Method for detecting content of thionafil derivative in food or Chinese patent medicine | 上海市食品药品检验研究院 | 2024-05-03 | — | — | CN | disclosed |