Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.45 |
| ▸ | NEK2 | P51955 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | PYGB | P11216 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL606993 | 0.88 | NEK2 (0.48) | OTUD7BNEK2CRBNPYGB | |
| Hydrochloric Acid SCHEMBL5612051 | 0.86 | NEK2 (0.47) | OTUD7BNEK2CRBNPYGB | |
| SCHEMBL15001635 | 0.84 | OTUD7B (0.46) | OTUD7BNEK2PYGB | |
| SCHEMBL1508957 | 0.79 | OTUD7B (0.53) | OTUD7BNEK2PYGB | |
| SCHEMBL21715595 | 0.75 | OTUD7B (0.50) | OTUD7BNEK2PYGB | |
| SCHEMBL2201251 | 0.74 | CRBN (0.38) | NEK2CRBNBACE1 | |
| SCHEMBL30239594 | 0.74 | OTUD7B (0.49) | OTUD7BNEK2PYGB | |
| Hydrochloric Acid SCHEMBL21292655 | 0.72 | CRBN (0.37) | NEK2CRBNBACE1 | |
| Hydrochloric Acid SCHEMBL31733116 | 0.72 | CRBN (0.37) | NEK2CRBNBACE1 | |
| SCHEMBL14377163 | 0.69 | OTUD7B (0.45) | OTUD7BPYGB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11952381-B2 | Cardiac sarcomere inhibitors | CYTOKINETICS, INC. (US) | 2024-04-09 | — | — | US | disclosed |
| US-20230090256-A1 | CARDIAC SARCOMERE INHIBITORS | CYTOKINETICS, INC. | 2023-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230090256-A1 | CARDIAC SARCOMERE INHIBITORS | TNNI3, MYLK2, TNNT2 | OTUD7B 2374/4885NEK2 1562/4885CRBN 1889/4885 |
| US-11952381-B2 | Cardiac sarcomere inhibitors | TNNI3, MYLK2, TNNT2 | OTUD7B 2374/4885NEK2 1562/4885CRBN 1889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.