SCHEMBL30200086

SCHEMBL30200086

[2H]c1ccc(Cl)c2ccoc12

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.37
CYP2A6 P11509 3/20 0.37
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
FTO Q9C0B1 1/20 0.36
FADS1 O60427 1/20 0.31
LMNA P02545 1/20 0.31
TSHR P16473 1/20 0.31
NR4A2 P43354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL827237 0.80 MAOA (0.50) CYP1A2CYP2A6MAOAMAOBFTO
SCHEMBL30200096 0.75 CYP2A6 (0.37) CYP1A2CYP2A6MAOAMAOBFTO
Chromone SCHEMBL30876963 0.69 MAOA (0.70) MAOAMAOBFTOLMNA
Chromone SCHEMBL31290986 0.65 MAOA (0.64) MAOAMAOBFTOLMNA
SCHEMBL1256888 0.65 AHR (0.41) CYP2A6MAOAMAOBFTOFADS1
SCHEMBL28143837 0.64 MAOA (0.47) CYP1A2CYP2A6MAOAMAOBFTO
SCHEMBL15019264 0.64 MAOA (0.33) MAOAMAOBFTOFADS1
SCHEMBL8799124 0.62 MAOA (0.40) CYP1A2CYP2A6MAOAMAOBFTO
Benzofuran SCHEMBL30390756 0.62
SCHEMBL17843510 0.61 CYP1A2 (0.39) CYP1A2CYP2A6LMNANR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023000834-A1 BENZIMIDAZOLE OR AZABENZIMIDAZOLE-6-CARBOXYLIC ACID COMPOUND AND USE THEREOF 广州必贝特医药股份有限公司 2023-01-26 WO disclosed