Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.64 |
| ▸ | MAOB | P27338 | 7/20 | 0.64 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.64 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chromone SCHEMBL30876963 | 0.88 | MAOA (0.70) | MAOAMAOBFTOGRM5KDM4E | |
| Chromone SCHEMBL30075941 | 0.79 | MAOA (1.00) | MAOAMAOBFTOGRM5KDM4E | |
| Chromone SCHEMBL29369932 | 0.79 | MAOA (1.00) | MAOAMAOBFTOGRM5KDM4E | |
| Chromone SCHEMBL37994 | 0.79 | MAOA (1.00) | MAOAMAOBFTOGRM5KDM4E | |
| Chromone SCHEMBL6347379 | 0.79 | MAOA (1.00) | MAOAMAOBFTOGRM5KDM4E | |
| Chromone SCHEMBL3203755 | 0.77 | MAOA (0.95) | MAOAMAOBFTOGRM5KDM4E | |
| Chromone SCHEMBL30865752 | 0.77 | MAOA (0.95) | MAOAMAOBFTOGRM5KDM4E | |
| Chromone SCHEMBL1034108 | 0.77 | MAOA (0.95) | MAOAMAOBFTOGRM5KDM4E | |
| Chromone SCHEMBL31622445 | 0.77 | MAOA (0.95) | MAOAMAOBFTOGRM5KDM4E | |
| Chromone SCHEMBL31277121 | 0.77 | MAOA (0.95) | MAOAMAOBFTOGRM5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118973616-A | Trkb ligand conjugated compounds and uses thereof | 阿达尔克斯制药有限公司 | 2024-11-15 | — | — | CN | disclosed |