Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.64 |
| ▸ | NCF1 | P14598 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2592802 | 1.00 | LOXL2 (0.64) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| Bromide SCHEMBL15618161 | 0.98 | LOXL2 (0.62) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL8762058 | 0.98 | LOXL2 (0.62) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| Benzene SCHEMBL6631416 | 0.98 | LOXL2 (0.62) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL1282250 | 0.85 | MAPT (0.54) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL27751565 | 0.83 | LOXL2 (0.60) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL16752130 | 0.83 | MAPT (0.52) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL334360 | 0.80 | LOXL2 (0.67) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL31599195 | 0.80 | LOXL2 (0.67) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| Bromide SCHEMBL9399386 | 0.78 | LOXL2 (0.64) | LOXL2NCF1HTR1AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594669-B | Parallel ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-115594669-A | Fused ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |