SCHEMBL30200271

SCHEMBL30200271

c1cccc[nH]cccccncccccnccc1

nearest known ligand 0.60

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.60
NAPRT Q6XQN6 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
ALDH1A1 P00352 1/20 0.33
FKBP5 Q13451 1/20 0.33
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
NOTUM Q6P988 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL20598704 1.00 TSHR (0.60) TSHRNAPRTTDP1ALDH1A1FKBP5
Pyridine SCHEMBL478481 1.00 TSHR (0.60) TSHRNAPRTTDP1ALDH1A1FKBP5
Pyridine SCHEMBL28139825 1.00 TSHR (0.60) TSHRNAPRTTDP1ALDH1A1FKBP5
Pyridine SCHEMBL28506684 0.97 TSHR (0.56) TSHRNAPRTTDP1ALDH1A1FKBP5
Pyridine SCHEMBL28095796 0.97 TSHR (0.56) TSHRNAPRTTDP1ALDH1A1FKBP5
Pyridine SCHEMBL25285631 0.97 TSHR (0.56) TSHRNAPRTTDP1ALDH1A1FKBP5
Pyridine SCHEMBL28100596 0.97 TSHR (0.56) TSHRNAPRTTDP1ALDH1A1FKBP5
Pyridine SCHEMBL28855134 0.97 TSHR (0.56) TSHRNAPRTTDP1ALDH1A1FKBP5
Pyridine SCHEMBL15676580 0.97 TSHR (0.56) TSHRNAPRTTDP1ALDH1A1FKBP5
Pyridine SCHEMBL28234777 0.97 TSHR (0.56) TSHRNAPRTTDP1ALDH1A1FKBP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230152226-A1 OPTICAL SENSORS LUMIRADX UK LTD (GB) 2023-05-18 US disclosed
EP-4121744-A1 OPTICAL SENSORS FOR DETECTING THE PRESENCE OR AMOUNT OF A TARGET PRESENT IN A SAMPLE LUMIRADX UK LTD (GB) 2023-01-25 EP disclosed