Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL20598704 | 1.00 | TSHR (0.60) | TSHRNAPRTTDP1ALDH1A1FKBP5 | |
| SCHEMBL30200271 | 1.00 | TSHR (0.60) | TSHRNAPRTTDP1ALDH1A1FKBP5 | |
| Pyridine SCHEMBL28139825 | 1.00 | TSHR (0.60) | TSHRNAPRTTDP1ALDH1A1FKBP5 | |
| Pyridine SCHEMBL28506684 | 0.97 | TSHR (0.56) | TSHRNAPRTTDP1ALDH1A1FKBP5 | |
| Pyridine SCHEMBL28095796 | 0.97 | TSHR (0.56) | TSHRNAPRTTDP1ALDH1A1FKBP5 | |
| Pyridine SCHEMBL25285631 | 0.97 | TSHR (0.56) | TSHRNAPRTTDP1ALDH1A1FKBP5 | |
| Pyridine SCHEMBL28100596 | 0.97 | TSHR (0.56) | TSHRNAPRTTDP1ALDH1A1FKBP5 | |
| Pyridine SCHEMBL28855134 | 0.97 | TSHR (0.56) | TSHRNAPRTTDP1ALDH1A1FKBP5 | |
| Pyridine SCHEMBL15676580 | 0.97 | TSHR (0.56) | TSHRNAPRTTDP1ALDH1A1FKBP5 | |
| Pyridine SCHEMBL28234777 | 0.97 | TSHR (0.56) | TSHRNAPRTTDP1ALDH1A1FKBP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4360 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478648-B | Pyridine pyrrole ruthenium-like complex, preparation method thereof and application of pyridine pyrrole ruthenium-like complex as electrocatalytic ammoxidation catalyst | 中南大学 | 2024-01-30 | — | — | CN | claimed |
| WO-2023165493-A1 | NAPHTHYRIDINE DERIVATIVE AND USE THEREOF | 武汉众诚康健生物医药科技有限公司 | 2023-09-07 | — | — | WO | claimed |
| CN-116673069-A | Ethylene selective trimerization catalyst system and process for the selective trimerization of ethylene | 山东京博石油化工有限公司 | 2023-09-01 | — | — | CN | claimed |
| CN-110437206-B | Molecular foldate of pyridine-pyrrole alternans and preparation method thereof | 上海大学 | 2022-06-10 | — | — | CN | claimed |
| CN-114478648-A | Pyridine-like pyrrole ruthenium complex, preparation method thereof and application of complex as electrocatalytic ammonia oxidation catalyst | 中南大学 | 2022-05-13 | — | — | CN | claimed |
| CN-110531007-A | A kind of quasi-arachidonic acid substance detection method | JIAXING MAIWEI METABOLIC BIOTECHNOLOGY CO LTD | 2019-12-03 | — | — | CN | claimed |
| CN-110536694-A | For treating pulmonary inflammatory composition and method | ATYR PHARMA INC | 2019-12-03 | — | — | CN | claimed |
| CN-110526915-A | A kind of preparation method of anaplastic lymphoma kinase inhibitor | SHOUYAO HOLDINGS BEIJING CO LTD | 2019-12-03 | — | — | CN | claimed |
| CN-110520503-A | Composition for organic electronic device | MERCK PATENT GMBH | 2019-11-29 | — | — | CN | claimed |
| CN-110494042-A | It is applied to the composition of the aerial part of plant | TERRAMERA EXCO HOLDINGS LTD | 2019-11-22 | — | — | CN | claimed |
| EP-2094712-A2 | COMPOUNDS USEFUL AS PROTEIN KINASE INHIBITORS | Vertex Pharmceuticals Incorporated (US) | 2009-09-02 | — | — | EP | claimed |
| CN-101326050-A | Multiaxial fabric | DU PONT (US) | 2008-12-17 | — | — | CN | claimed |
| EP-1997475-A2 | Composition comprising at least one substituted derivative of acetylenic carbocyanine, method of treating keratinous fibres implementing it and device | L'Oréal (FR) | 2008-12-03 | — | — | EP | claimed |
| WO-2008060597-A2 | COMPOUNDS USEFUL AS PROTEIN KINASE INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-05-22 | — | — | WO | claimed |
| US-20070232661-A1 | Hedgehog Pathway Antagonists | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-10-04 | — | — | US | claimed |
| CN-1909908-A | Pyrazolo [1, 5-a ] pyrimidin-7-yl-amine derivatives for the treatment of protein kinase dependent diseases | NOVARTIS AG (CH) | 2007-02-07 | — | — | CN | claimed |
| WO-2005033288-A2 | HEDGEHOG PATHWAY ANTAGONISTS | THE JOHNS HOPKINS UNIVERSITY (US) | 2005-04-14 | — | — | WO | claimed |
| US-6613537-B2 | Diagnosis of diabetes | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2003-09-02 | — | — | US | claimed |
| US-20020028464-A1 | Pyrrolopyridinium derivatives | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2002-03-07 | — | — | US | claimed |
| EP-1130021-A2 | Pyrrolopyridinium derivatives | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2001-09-05 | — | — | EP | claimed |