SCHEMBL302006

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3379804	0.87	LMNA (0.57)	MAPTLMNAALDH1A1OXTRKMT2A
	SCHEMBL302225	0.82	LMNA (0.60)	MAPTLMNAALDH1A1KMT2AMEN1
	SCHEMBL304042	0.79	MAPT (0.46)	MAPTLMNACTSDBACE1BACE2
	SCHEMBL302764	0.79	MAPT (0.48)	MAPTLMNACTSDBACE1BACE2
	SCHEMBL3376926	0.78	MAPT (0.60)	MAPTLMNAALDH1A1KMT2AMEN1
	SCHEMBL303030	0.77	GRM2 (0.54)	MAPTLMNAALDH1A1KMT2AGRM2
	SCHEMBL3379839	0.77	LMNA (0.56)	MAPTLMNAALDH1A1KMT2AMEN1
	SCHEMBL302565	0.77	MAPT (0.45)	MAPTLMNACTSDBACE1BACE2
	SCHEMBL3376222	0.77	MAPT (0.45)	MAPTLMNACTSDBACE1BACE2
	SCHEMBL2185822	0.76	RAB9A (0.59)	MAPTLMNAALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.