Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4221177 | 1.00 | GAA (0.47) | GAAALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL30375313 | 0.83 | GAA (0.53) | GAAALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL2570420 | 0.83 | GAA (0.53) | GAAALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL5106192 | 0.82 | ALDH1A1 (0.47) | GAAALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL5106197 | 0.82 | ALDH1A1 (0.47) | GAAALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL18026637 | 0.80 | GAA (0.56) | GAAALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL28678791 | 0.78 | ALDH1A1 (0.49) | GAAALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL20456889 | 0.76 | ALDH1A1 (0.54) | GAAALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL4764806 | 0.76 | ALDH1A1 (0.43) | GAAALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL22833063 | 0.76 | GAA (0.51) | GAAALDH1A1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109422749-B | Pyrimidinedione derivative for inhibiting monocarboxylic acid transporter | 重庆医药工业研究院有限责任公司 | 2023-01-24 | — | — | CN | disclosed |