Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | VDR | P11473 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2570420 | 1.00 | GAA (0.53) | GAAALDH1A1CYP1A2CYP2C9MAPT | |
| SCHEMBL18026637 | 0.85 | GAA (0.56) | GAAALDH1A1CYP1A2CYP2C9MAPT | |
| SCHEMBL28678791 | 0.83 | ALDH1A1 (0.49) | GAAALDH1A1CYP1A2CYP2C9MAPT | |
| SCHEMBL30200909 | 0.83 | GAA (0.47) | GAAALDH1A1CYP1A2CYP2C9MAPT | |
| SCHEMBL4221177 | 0.83 | GAA (0.47) | GAAALDH1A1CYP1A2CYP2C9MAPT | |
| SCHEMBL2570416 | 0.83 | GAA (0.59) | GAAALDH1A1CYP1A2CYP2C9MAPT | |
| SCHEMBL20456889 | 0.81 | ALDH1A1 (0.54) | GAAALDH1A1CYP1A2CYP2C9MAPT | |
| Methyl Alcohol SCHEMBL28761646 | 0.81 | GAA (0.51) | GAAALDH1A1CYP1A2CYP2C9MAPT | |
| SCHEMBL22833063 | 0.81 | GAA (0.51) | GAAALDH1A1CYP1A2CYP2C9MAPT | |
| SCHEMBL18652223 | 0.81 | GAA (0.51) | GAAALDH1A1CYP1A2CYP2C9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122010947-A | Antagonists of adenosine A2a receptors | 阿道尔克斯治疗有限公司 | 2026-05-12 | — | — | CN | disclosed |
| CN-115996929-A | Antagonists of adenosine A2a receptors | 阿道尔克斯治疗有限公司 | 2023-04-21 | — | — | CN | disclosed |