Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 15/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25089767 | 1.00 | P2RX7 (0.42) | P2RX7SLC6A2SLC6A4IDO1DPP4 | |
| SCHEMBL30202136 | 0.81 | TRPV1 (0.43) | P2RX7SLC6A2SLC6A4 | |
| SCHEMBL27664417 | 0.81 | P2RX7 (0.42) | P2RX7SLC6A2SLC6A4IDO1DPP4 | |
| SCHEMBL15532421 | 0.81 | TRPV1 (0.43) | P2RX7SLC6A2SLC6A4 | |
| SCHEMBL25089766 | 0.81 | P2RX7 (0.46) | P2RX7SLC6A2SLC6A4 | |
| SCHEMBL28000644 | 0.81 | P2RX7 (0.46) | P2RX7SLC6A2SLC6A4IDO1DPP4 | |
| SCHEMBL7330366 | 0.80 | IDO1 (0.52) | IDO1 | |
| Hydrochloric Acid SCHEMBL5705707 | 0.80 | TAAR1 (0.56) | P2RX7SLC6A2SLC6A4IDO1 | |
| SCHEMBL10540791 | 0.79 | P2RX7 (0.46) | P2RX7SLC6A2SLC6A4IDO1NOTUM | |
| SCHEMBL7545968 | 0.79 | IDO1 (0.50) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023028056-A1 | 3-AMINO PIPERIDYL SODIUM CHANNEL INHIBITORS | GENENTECH, INC. (US) | 2023-03-02 | — | — | WO | disclosed |