Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLQ | O75417 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330366 | 0.98 | IDO1 (0.52) | IDO1DAOALDH1A1KDM4EATM | |
| SCHEMBL17329111 | 0.84 | IDO1 (0.59) | IDO1DAOALDH1A1KDM4EATM | |
| SCHEMBL21312960 | 0.84 | HDAC1 (0.50) | IDO1DAOALDH1A1KDM4EATM | |
| SCHEMBL1043985 | 0.81 | IDO1 (0.52) | IDO1DAOALDH1A1KDM4EATM | |
| SCHEMBL23337251 | 0.80 | IDO1 (0.55) | IDO1DAOALDH1A1KDM4EATM | |
| SCHEMBL25089767 | 0.79 | P2RX7 (0.42) | IDO1 | |
| SCHEMBL30201209 | 0.79 | P2RX7 (0.42) | IDO1 | |
| SCHEMBL2089439 | 0.78 | IDO1 (0.53) | IDO1DAOALDH1A1KDM4EATM | |
| SCHEMBL1043968 | 0.78 | HDAC1 (0.51) | IDO1DAOALDH1A1KDM4EATM | |
| SCHEMBL5609142 | 0.77 | IDO1 (0.52) | IDO1DAOALDH1A1KDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482990-B1 | Prostaglandin E analogues | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2002-11-19 | — | — | US | disclosed |
| EP-1211241-A1 | PROSTAGLANDIN E ANALOGUES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2002-06-05 | — | — | EP | disclosed |