SCHEMBL30201447

SCHEMBL30201447

CCCOc1ccc(C2CCC(C3CCC(CCC)CC3)CC2)c(F)c1F

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 4/20 0.35
HTR2B P41595 4/20 0.35
HTR2A P28223 1/20 0.35
CYP2C9 P11712 1/20 0.34
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.33
LMNA P02545 1/20 0.33
MEN1 O00255 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
OPRL1 P41146 7/20 0.32
FPR2 P25090 2/20 0.32
HTR1D P28221 2/20 0.32
HTR1B P28222 2/20 0.32
HTT P42858 1/20 0.31
TLR4 O00206 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12140864 1.00 HTR2C (0.35) HTR2CHTR2BHTR2ACYP2C9ALDH1A1
SCHEMBL7858136 1.00 HTR2C (0.35) HTR2CHTR2BHTR2ACYP2C9ALDH1A1
SCHEMBL9631987 0.96 HTR2C (0.37) HTR2CHTR2BHTR2ACYP2C9ALDH1A1
SCHEMBL9631990 0.96 HTR2C (0.37) HTR2CHTR2BHTR2ACYP2C9ALDH1A1
SCHEMBL15803732 0.95 MCHR1 (0.34) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL9632723 0.95 HTR2C (0.36) HTR2CHTR2BHTR2ACYP2C9ALDH1A1
SCHEMBL9632717 0.95 HTR2C (0.36) HTR2CHTR2BHTR2ACYP2C9ALDH1A1
SCHEMBL14235296 0.94 SCN9A (0.36) HTR2CCYP2C9ALDH1A1MAPTLMNA
SCHEMBL26209558 0.94 SCN9A (0.36) HTR2CCYP2C9ALDH1A1MAPTLMNA
SCHEMBL14922626 0.94 HTR2C (0.34) HTR2CHTR2BHTR2AALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023005682-A1 METHOD FOR ANALYZING TARGETED EXPOSURE GROUP OF ENVIRONMENTAL POLLUTANTS IN PLASMA, AND USE THEREOF 暨南大学 2023-02-02 WO claimed
CN-113671068-B Method for analyzing environmental pollutant targeted exposure group in blood plasma and application thereof 暨南大学 2023-01-24 CN disclosed