Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.35 |
| ▸ | HTR2B | P41595 | 4/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.32 |
| ▸ | FPR2 | P25090 | 2/20 | 0.32 |
| ▸ | HTR1D | P28221 | 2/20 | 0.32 |
| ▸ | HTR1B | P28222 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TLR4 | O00206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30201447 | 1.00 | HTR2C (0.35) | HTR2CHTR2BHTR2ACYP2C9ALDH1A1 | |
| SCHEMBL12140864 | 1.00 | HTR2C (0.35) | HTR2CHTR2BHTR2ACYP2C9ALDH1A1 | |
| SCHEMBL9631987 | 0.96 | HTR2C (0.37) | HTR2CHTR2BHTR2ACYP2C9ALDH1A1 | |
| SCHEMBL9631990 | 0.96 | HTR2C (0.37) | HTR2CHTR2BHTR2ACYP2C9ALDH1A1 | |
| SCHEMBL15803732 | 0.95 | MCHR1 (0.34) | CYP2C9ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL9632723 | 0.95 | HTR2C (0.36) | HTR2CHTR2BHTR2ACYP2C9ALDH1A1 | |
| SCHEMBL9632717 | 0.95 | HTR2C (0.36) | HTR2CHTR2BHTR2ACYP2C9ALDH1A1 | |
| SCHEMBL14235296 | 0.94 | SCN9A (0.36) | HTR2CCYP2C9ALDH1A1MAPTLMNA | |
| SCHEMBL26209558 | 0.94 | SCN9A (0.36) | HTR2CCYP2C9ALDH1A1MAPTLMNA | |
| SCHEMBL14922626 | 0.94 | HTR2C (0.34) | HTR2CHTR2BHTR2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197217-B1 | EXHIBIT A NEGATIVE DIELECTRIC ANISOTROPY VALUE, HAVE AN EXTREMELY HIGH VOLTAGE HOLDING RATIO AND A LOW THRESHOLD VOLTAGE, SMALL DEPENDENCY ON TEMPERATURE, HARDLY EXHIBIT SMECTIC PHASE; EXCELLENT IN MISCIBILITY WITH OTHER LC'S | CHISSO CORPORATION (JP) | 2001-03-06 | — | — | US | disclosed |
| EP-0959061-A1 | 3,3'-DIFLUOROBIPHENYL DERIVATIVES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY ELEMENTS | CHISSO CORPORATION (JP) | 1999-11-24 | — | — | EP | disclosed |