SCHEMBL9631990

SCHEMBL9631990

CCCOc1ccc(C2CCC(CCC)CC2)c(F)c1F

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 4/20 0.37
HTR2B P41595 4/20 0.37
HTR2A P28223 1/20 0.37
CYP2C9 P11712 1/20 0.36
ALDH1A1 P00352 2/20 0.35
MAPT P10636 2/20 0.35
LMNA P02545 1/20 0.35
MEN1 O00255 1/20 0.35
MAPK1 P28482 1/20 0.35
KMT2A Q03164 1/20 0.35
OPRL1 P41146 8/20 0.34
FPR2 P25090 2/20 0.33
HTR1D P28221 2/20 0.33
HTR1B P28222 2/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9631987 1.00 HTR2C (0.37) HTR2CHTR2BHTR2ACYP2C9ALDH1A1
SCHEMBL9632717 0.99 HTR2C (0.36) HTR2CHTR2BHTR2ACYP2C9ALDH1A1
SCHEMBL9632723 0.99 HTR2C (0.36) HTR2CHTR2BHTR2ACYP2C9ALDH1A1
SCHEMBL30201447 0.96 HTR2C (0.35) HTR2CHTR2BHTR2ACYP2C9ALDH1A1
SCHEMBL12140864 0.96 HTR2C (0.35) HTR2CHTR2BHTR2ACYP2C9ALDH1A1
SCHEMBL7858136 0.96 HTR2C (0.35) HTR2CHTR2BHTR2ACYP2C9ALDH1A1
SCHEMBL14235005 0.95 FPR2 (0.37) HTR2CHTR2BHTR2ACYP2C9ALDH1A1
SCHEMBL17900180 0.93 CYP2C9 (0.35) HTR2CHTR2BHTR2ACYP2C9ALDH1A1
SCHEMBL4402652 0.93 SCN9A (0.38) HTR2CCYP2C9ALDH1A1MAPTLMNA
SCHEMBL26209537 0.93 SCN9A (0.38) HTR2CCYP2C9ALDH1A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240067879-A1 Liquid-crystal medium MERCK PATENT GMBH (DE) 2024-02-29 US disclosed
US-20230383186-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2023-11-30 US disclosed
US-20230357637-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2023-11-09 US disclosed
US-20230323209-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2023-10-12 US disclosed
US-20230272282-A1 LC MIXTURES WITH NEGATIVE DELTA EPSILONCONTAINING CC-4-V1 AND COB(S)-N-OM MERCK PATENT GMBH (DE) 2023-08-31 US disclosed
US-20230265345-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND APPLICATION OF LIQUID CRYSTAL COMPOSITION BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) 2023-08-24 US disclosed
US-20230183572-A1 LIQUID CRYSTAL COMPOSITION WITH GOOD FREQUENCY DEPENDENCE AND LIQUID CRYSTAL DISPLAY ELEMENT SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2023-06-15 US disclosed
US-10907101-B2 Liquid crystal cell and liquid crystal display SHARP KABUSHIKI KAISHA (JP) 2021-02-02 US disclosed
US-20190093016-A1 LIQUID CRYSTAL CELL AND LIQUID CRYSTAL DISPLAY SHARP KABUSHIKI KAISHA (JP) 2019-03-28 US disclosed
EP-0364538-B1 DIFLUOROBENZOL DERIVATIVES MERCK PATENT GmbH (DE) 1992-05-06 EP disclosed