Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.36 |
| ▸ | HTR3B | O95264 | 2/20 | 0.36 |
| ▸ | HTR3A | P46098 | 2/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11884015 | 0.85 | TSHR (0.37) | ALDH1A1TDP1MAPK1HTR3EHTR3B | |
| SCHEMBL10478101 | 0.82 | MEN1 (0.47) | ALDH1A1TP53TDP1MAPK1HTR3E | |
| SCHEMBL27637733 | 0.81 | ALDH1A1 (0.39) | ALDH1A1TP53TDP1MAPK1HTR3E | |
| SCHEMBL28260621 | 0.71 | KMT2A (0.63) | ALDH1A1TP53TSHRRAB9ANPC1 | |
| SCHEMBL28260620 | 0.71 | KMT2A (0.63) | ALDH1A1TP53TSHRRAB9ANPC1 | |
| SCHEMBL699001 | 0.71 | ALDH1A1 (0.68) | ALDH1A1TP53TDP1MAPK1TSHR | |
| SCHEMBL3019453 | 0.70 | ALDH1A1 (0.43) | ALDH1A1TDP1TSHRRAB9ANPC1 | |
| SCHEMBL9618406 | 0.70 | TSHR (0.45) | ALDH1A1TP53TDP1TSHRRAB9A | |
| SCHEMBL5183277 | 0.70 | ALDH1A1 (0.42) | ALDH1A1TP53TDP1MAPK1TSHR | |
| SCHEMBL17142429 | 0.70 | HSD17B10 (0.52) | ALDH1A1TP53TSHRPOLBCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389767-B2 | Processes and compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-05 | — | — | US | claimed |
| US-20100204504-A1 | NOVEL PROCESSES AND COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-12 | — | — | US | claimed |
| EP-2183212-A1 | NOVEL PROCESSES AND COMPOUNDS | Syngenta Participations AG (CH) | 2010-05-12 | — | — | EP | claimed |
| WO-2009030457-A1 | NOVEL PROCESSES AND COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-03-12 | — | — | WO | claimed |
| US-8389767-B2 | Processes and compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-05 | — | — | US | disclosed |
| US-20100204504-A1 | NOVEL PROCESSES AND COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204504-A1 | NOVEL PROCESSES AND COMPOUNDS | DDT, CYP4B1, CYP4F3 | ALDH1A1 351/4885TP53 4488/4885TDP1 2351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.