Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.36 |
| ▸ | HTR3B | O95264 | 2/20 | 0.36 |
| ▸ | HTR3A | P46098 | 2/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3020159 | 0.85 | ALDH1A1 (0.37) | TSHRSMN1; SMN2MAPTKDM4EMAPK1 | |
| SCHEMBL10478148 | 0.82 | MEN1 (0.43) | TSHRCASP1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL28234558 | 0.75 | MEN1 (0.55) | SMN1; SMN2MAPTKDM4EMAPK1TDP1 | |
| SCHEMBL1164647 | 0.72 | TSHR (0.42) | TSHRCASP1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL5732135 | 0.71 | SMN1; SMN2 (0.68) | TSHRCASP1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL107060 | 0.71 | SMN1; SMN2 (0.68) | TSHRCASP1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL3019453 | 0.70 | ALDH1A1 (0.43) | TSHRSMN1; SMN2MAPTTDP1ALDH1A1 | |
| SCHEMBL5183277 | 0.70 | ALDH1A1 (0.42) | TSHRSMN1; SMN2MAPTMAPK1TDP1 | |
| SCHEMBL13069724 | 0.70 | HSD17B10 (0.52) | TSHRCASP1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL101687 | 0.70 | TSHR (0.45) | TSHRCASP1SMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3943110-A | Fiber and film-forming nuclearly-halogenated poly(1,4-benzamides) | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-03-09 | — | — | US | disclosed |