Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | METAP2 | P50579 | 2/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26094704 | 1.00 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL25151359 | 0.79 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL23723648 | 0.78 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL23723651 | 0.78 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL30169603 | 0.77 | NOS1 (0.42) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL14995475 | 0.77 | AXL (0.51) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL25470649 | 0.77 | NOS1 (0.42) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL28900790 | 0.74 | KDM4E (0.33) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL21593366 | 0.73 | CHEK1 (0.48) | PIM1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL31082552 | 0.72 | AXL (0.58) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4387609-A2 | ARYL SULFONYL (HYDROXY) PIPERIDINES AS CCR6 INHIBITORS | ChemoCentryx, Inc. (US) | 2024-06-26 | — | — | EP | disclosed |
| WO-2023023532-A2 | ARYL SULFONYL (HYDROXY) PIPERIDINES AS CCR6 INHIBITORS | CHEMOCENTRYX, INC. (US) | 2023-02-23 | — | — | WO | disclosed |