Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.48 |
| ▸ | KDM4A | O75164 | 2/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.48 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.48 |
| ▸ | TET3 | O43151 | 1/20 | 0.48 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16428981 | 1.00 | GPR84 (0.58) | GPR84FFAR1BLMTET2KDM4A | |
| SCHEMBL14661633 | 1.00 | GPR84 (0.58) | GPR84FFAR1BLMTET2KDM4A | |
| SCHEMBL28704367 | 0.95 | GPR84 (0.64) | GPR84FFAR1BLMTET2KDM4A | |
| SCHEMBL9446362 | 0.93 | GPR84 (0.68) | GPR84FFAR1BLMTET2KDM4A | |
| SCHEMBL22634111 | 0.93 | GPR84 (0.68) | GPR84FFAR1BLMTET2KDM4A | |
| SCHEMBL4626344 | 0.93 | GPR84 (0.68) | GPR84FFAR1BLMTET2KDM4A | |
| SCHEMBL6555168 | 0.93 | GPR84 (0.68) | GPR84FFAR1BLMTET2KDM4A | |
| SCHEMBL28615741 | 0.93 | GPR84 (0.68) | GPR84FFAR1BLMTET2KDM4A | |
| SCHEMBL6037095 | 0.93 | GPR84 (0.68) | GPR84FFAR1BLMTET2KDM4A | |
| SCHEMBL27780074 | 0.93 | GPR84 (0.68) | GPR84FFAR1BLMTET2KDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007785-A2 | Skin treatment compositions, process for their preparation and applicator containing these compositions | UNILEVER PLC (GB) | 1980-02-06 | — | — | EP | claimed |
| US-12053465-B2 | KCC2 expression enhancing compounds and uses thereof | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2024-08-06 | — | — | US | disclosed |
| US-20220378782-A1 | KCC2 EXPRESSION ENHANCING COMPOUNDS AND USES THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2022-12-01 | — | — | US | disclosed |
| US-11331313-B2 | KCC2 expression enhancing compounds and uses thereof | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2022-05-17 | — | — | US | disclosed |
| US-20200085817-A1 | KCC2 EXPRESSION ENHANCING COMPOUNDS AND USES THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2020-03-19 | — | — | US | disclosed |
| WO-2020039768-A1 | POLYMER PRODUCTION METHOD | 東亞合成株式会社 | 2020-02-27 | — | — | WO | disclosed |
| WO-2018217766-A1 | KCC2 EXPRESSION ENHANCING COMPOUNDS AND USES THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2018-11-29 | — | — | WO | disclosed |
| US-20150038333-A1 | PLANT PROTECTIVE COMPOSITION CONTAINING ALPHA-HYDROXY ACIDS | HELMHOLTZ ZENTRUM MÜNCHEN DEUTSCHES FORSCHUNGSZENT -RUN FÜR GESUNDHEIT UND (DE) | 2015-02-05 | — | — | US | disclosed |
| EP-2736331-A1 | PLANT PROTECTIVE COMPOSITION CONTAINING ALPHA-HYDROXY ACIDS | Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2014-06-04 | — | — | EP | disclosed |
| WO-2013014245-A1 | PLANT PROTECTIVE COMPOSITION CONTAINING ALPHA-HYDROXY ACIDS | HELMHOLTZ ZENTRUM MÜNCHEN DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH) (DE) | 2013-01-31 | — | — | WO | disclosed |
| US-6197343-B1 | GRANULES AND BLOOD CIRCULATION ACCELERATION FOR SKINS | KAO CORPORATION (JP) | 2001-03-06 | — | — | US | disclosed |
| US-6063366-A | WATER INSOLUBLE PARTICLES IN BINDER | KAO CORPORATION (JP) | 2000-05-16 | — | — | US | disclosed |
| EP-0965328-A1 | COSMETIC | Kao Corporation (JP) | 1999-12-22 | — | — | EP | disclosed |
| EP-0904772-A1 | SKIN COLOR IMPROVER | Kao Corporation (JP) | 1999-03-31 | — | — | EP | disclosed |
| EP-0872228-A1 | COSMETOLOGICAL METHODS | Kao Corporation (JP) | 1998-10-21 | — | — | EP | disclosed |
| EP-0575844-B1 | Hydroxamic acid derivatives and pharmaceutical compositions thereof | HOFFMANN LA ROCHE (CH) | 1998-01-21 | — | — | EP | disclosed |
| CN-1165521-A | Phenyl peptides, method for preparing same, and pharmaceutical compositions containing said peptides | LAPHAL LABORATOIRES SA (FR) | 1997-11-19 | — | — | CN | disclosed |
| EP-0575844-A2 | Hydroxamic acid derivatives and pharmaceutical compositions thereof | F. HOFFMANN-LA ROCHE AG (CH) | 1993-12-29 | — | — | EP | disclosed |
| EP-0374097-A2 | Use of peptide isosteres as retroviral protease inhibitors | CIBA-GEIGY AG (CH) | 1990-06-20 | — | — | EP | disclosed |
| US-4424234-A | A-HYDROXYCAPROIC ACID OR A-HYDROXYCAPRYLIC ACID | LEVER BROTHERS COMPANY (US) | 1984-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11331313-B2 | KCC2 expression enhancing compounds and uses thereof | MECP2, SLC1A2, GRIN2C | GPR84 791/4885FFAR1 3759/4885BLM 2534/4885 |
| US-20200085817-A1 | KCC2 EXPRESSION ENHANCING COMPOUNDS AND USES THEREOF | MECP2, SLC1A2, GRIN2C | GPR84 791/4885FFAR1 3759/4885BLM 2534/4885 |
| US-20220378782-A1 | KCC2 EXPRESSION ENHANCING COMPOUNDS AND USES THEREOF | MECP2, SLC1A2, GRIN2C | GPR84 791/4885FFAR1 3759/4885BLM 2534/4885 |
| US-20150038333-A1 | PLANT PROTECTIVE COMPOSITION CONTAINING ALPHA-HYDROXY ACIDS | HAO1, HAAO, HAO2 | GPR84 2235/4885FFAR1 197/4885BLM 3148/4885 |
| US-12053465-B2 | KCC2 expression enhancing compounds and uses thereof | MECP2, SLC1A2, GRIN2C | GPR84 791/4885FFAR1 3759/4885BLM 2534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.