⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30334802 | 0.78 | LMNA (0.43) | — | |
| SCHEMBL121647 | 0.78 | LMNA (0.43) | — | |
| Hydrochloric Acid SCHEMBL11520836 | 0.76 | LMNA (0.41) | — | |
| Cyclohexane SCHEMBL23674790 | 0.71 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL30587754 | 0.70 | ITGB2 (0.65) | — | |
| SCHEMBL3075319 | 0.70 | — | — | |
| SCHEMBL30313796 | 0.70 | — | — | |
| Dioxane SCHEMBL23674718 | 0.69 | LMNA (0.62) | — | |
| SCHEMBL31043065 | 0.67 | GPR3 (0.35) | — | |
| Pyrazine SCHEMBL22491600 | 0.67 | NOTUM (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230065368-A1 | INHIBITING UBIQUITIN SPECIFIC PEPTIDASE 9X | FORMA THERAPEUTICS, INC. | 2023-03-02 | — | — | US | disclosed |