Glycine

Glycine

SCHEMBL30204

CCO.NCC(=O)O.NCC(=O)O

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D

The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4A known ✓ P27815 1/20 0.35
PDE3A known ✓ Q14432 1/20 0.35
OR51E2 Q9H255 2/20 0.71
GLRA1 P23415 1/20 0.71
SLC6A9 P48067 1/20 0.71
FFAR3 O14843 2/20 0.50
TSHR P16473 5/20 0.43
GABRR1 P24046 3/20 0.43
ALDH1A1 P00352 3/20 0.43
HDAC3 O15379 2/20 0.42
HDAC1 Q13547 2/20 0.42
HDAC2 Q92769 2/20 0.42
HDAC8 Q9BY41 2/20 0.42
HDAC11 Q96DB2 5/20 0.38
LMNA P02545 2/20 0.38
BLM P54132 2/20 0.38
KMT2A Q03164 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
GABRR3 A8MPY1 1/20 0.38
GABRP O00591 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycine SCHEMBL723130 1.00
Glycine SCHEMBL468791 1.00 OR51E2 (0.71) OR51E2GLRA1SLC6A9FFAR3TSHR
Glycine SCHEMBL2418117 0.97 OR51E2 (0.67) OR51E2GLRA1SLC6A9FFAR3TSHR
Glycine SCHEMBL28367785 0.97
Glycine SCHEMBL19208039 0.94 GLRA1 (0.62) OR51E2GLRA1SLC6A9FFAR3TSHR
Glycine SCHEMBL5535262 0.94 GLRA1 (0.62) OR51E2GLRA1SLC6A9FFAR3TSHR
Glycine SCHEMBL2361724 0.89
Glycine SCHEMBL28449741 0.89
Glycine SCHEMBL29129757 0.89
Glycine SCHEMBL2687281 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5597 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4660233-A1 COMPOSITION OF SUPER ABSORBENT POLYMER AND PREPARATION METHOD THEREOF LG CHEM, LTD. (KR) 2025-12-10 EP claimed
CN-119546691-A Superabsorbent polymer composition and method of making same 株式会社LG化学 2025-02-28 CN claimed
WO-2024253442-A1 COMPOSITION OF SUPER ABSORBENT POLYMER AND PREPARATION METHOD THEREOF 주식회사 엘지화학 2024-12-12 WO claimed
WO-2024172530-A1 SUPER ABSORBENT POLYMER AND PREPARATION METHOD THEREOF 주식회사 엘지화학 2024-08-22 WO claimed
WO-2024172277-A1 SUPERABSORBENT POLYMER COMPOSITION AND PREPARATION METHOD THEREOF 주식회사 엘지화학 2024-08-22 WO claimed
US-20240150237-A1 GRINDING STABILIZING ADDITIVE FOR VERTICAL ROLLER MILLS GCP APPLIED TECH INC (US) 2024-05-09 US claimed
EP-4358926-A1 COMPOSITION FOR CLEANSING AND/OR REMOVING MAKEUPS FROM KERATIN MATERIALS L'OREAL (FR) 2024-05-01 EP claimed
EP-4352191-A1 BIO-BASED CLEANER ADDITIVE Solugen, Inc. (US) 2024-04-17 EP claimed
WO-2024065609-A1 COMPOSITION FOR CARING FOR KERATIN MATERIALS AND MASK CONTAINING THE SAME L'OREAL (FR) 2024-04-04 WO claimed
EP-4312537-A1 QUAT-FREE POWDERED DISINFECTANT/SANITIZER Sterilex LLC (US) 2024-02-07 EP claimed
EP-0265187-A2 Detergent plus softener with imidazoline ingredient THE PROCTER & GAMBLE COMPANY (US) 1988-04-27 EP claimed
EP-0145506-B1 ELIMINATION OF DEFECTS IN CYSTEINE-SENSITIZED EMULSIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-03-02 EP claimed
US-4698090-A Process for preparation of compositions for modifying plant growth; compositions for plant growth modification; and method for the use thereof PACIFIC MICRO MINERALS, INC. (US) 1987-10-06 US claimed
US-4687592-A ETHER POLYCARBOXYLATE, CHELATING AGENT, DISPERSANT THE PROCTER & GAMBLE COMPANY (US) 1987-08-18 US claimed
EP-0192442-A2 Detergency builder system THE PROCTER & GAMBLE COMPANY (US) 1986-08-27 EP claimed
EP-0145506-A2 Elimination of defects in cysteine-sensitized emulsions E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-06-19 EP claimed
EP-0140519-A1 Use of chelating agents in water desalination PFIZER INC. (US) 1985-05-08 EP claimed
US-4514492-A Elimination of defects in cysteine-sensitized emulsions E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-04-30 US claimed
US-4359093-A AQUEOUS SLUG OF ALKALINE MATERIAL AND A CHELATING AMINOPOLYCARBOXYLIC ACID OR SALT UNION OIL CO. OF CALIFORNIA (US) 1982-11-16 US claimed
US-4036300-A AMINOPOLYCARBOXYLIC ACIDS AND SALTS AS CHELATING AGENTS UNION OIL COMPANY OF CALIFORNIA (US) 1977-07-19 US claimed