Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A known ✓ | P27815 | 1/20 | 0.35 |
| ▸ | PDE3A known ✓ | Q14432 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.71 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.71 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.71 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL723130 | 1.00 | — | — | |
| Glycine SCHEMBL30204 | 1.00 | OR51E2 (0.71) | OR51E2GLRA1SLC6A9FFAR3TSHR | |
| Glycine SCHEMBL2418117 | 0.97 | OR51E2 (0.67) | OR51E2GLRA1SLC6A9FFAR3TSHR | |
| Glycine SCHEMBL28367785 | 0.97 | — | — | |
| Glycine SCHEMBL19208039 | 0.94 | GLRA1 (0.62) | OR51E2GLRA1SLC6A9FFAR3TSHR | |
| Glycine SCHEMBL5535262 | 0.94 | GLRA1 (0.62) | OR51E2GLRA1SLC6A9FFAR3TSHR | |
| Glycine SCHEMBL2361724 | 0.89 | — | — | |
| Glycine SCHEMBL28449741 | 0.89 | — | — | |
| Glycine SCHEMBL29129757 | 0.89 | — | — | |
| Glycine SCHEMBL2687281 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 395 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10543482-B2 | Catalyst solution for electroless plating | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2020-01-28 | — | — | US | claimed |
| EP-2868771-B1 | Catalyst solution for electroless plating and method for electroless plating | ROHM & HAAS ELECT MAT (US) | 2018-04-25 | — | — | EP | claimed |
| CN-107761123-A | A kind of environmentally friendly oil pipeline cleaning agent | 广州迪奕科环保科技有限公司 | 2018-03-06 | — | — | CN | claimed |
| CN-106414693-A | Compositions and methods useful for removing tablet coatings | 艺康美国股份有限公司 | 2017-02-15 | — | — | CN | claimed |
| WO-2016083827-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AN ARTEMISININ DERIVATIVE FOR NASAL OR PULMONARY DELIVERY | CIPLA LIMITED (IN) | 2016-06-02 | — | — | WO | claimed |
| EP-2868771-A1 | Catalyst solution for electroless plating and method for electroless plating | Rohm and Haas Electronic Materials LLC (US) | 2015-05-06 | — | — | EP | claimed |
| US-20150118406-A1 | CATALYST SOLUTION FOR ELECTROLESS PLATING | ROHM AND HAAS ELECTRONIC MATERIALS LLC | 2015-04-30 | — | — | US | claimed |
| CN-101822932-B | Composite decarbonization solvent for eliminating carbon dioxide in natural gases | CN PETROLEUM ENG CO LTD | 2013-01-02 | — | — | CN | claimed |
| CN-101822932-A | Composite decarbonization solvent for eliminating carbon dioxide in natural gases | CN PETROLEUM ENG CO LTD | 2010-09-08 | — | — | CN | claimed |
| EP-1489909-A1 | TRANSITION METAL CHELATES AS SELECTIVE HERBICIDE | W. NEUDORFF GmbH KG (DE) | 2004-12-29 | — | — | EP | claimed |
| EP-0058430-B1 | DYESTUFF-CONTAINING MICROSCOPIC CAPSULE DISPERSION FOR RECORD MATERIALS | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-12-04 | — | — | EP | claimed |
| EP-0054277-B1 | DYESTUFF-CONTAINING MICROSCOPIC CAPSULE SUSPENSION FOR RECORD MATERIALS | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-07-03 | — | — | EP | claimed |
| EP-0140519-A1 | Use of chelating agents in water desalination | PFIZER INC. (US) | 1985-05-08 | — | — | EP | claimed |
| US-4480002-A | LACTONE DYES AND A SEQUESTERING AGENT; DISCOLORATION INMIBITION; CARBONLESS PAPER | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1984-10-30 | — | — | US | claimed |
| US-4384871-A | Dyestuff-containing microscopic capsule dispersion for record materials | MITSUI TOATSU CHEMICALS, INC. (JP) | 1983-05-24 | — | — | US | claimed |
| EP-0058430-A1 | Dyestuff-containing microscopic capsule dispersion for record materials | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1982-08-25 | — | — | EP | claimed |
| EP-0054277-A2 | Dyestuff-containing microscopic capsule suspension for record materials | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1982-06-23 | — | — | EP | claimed |
| US-4284435-A | Method for spray cleaning painted surfaces | S. C. JOHNSON & SON, INC. (US) | 1981-08-18 | — | — | US | claimed |
| US-4173521-A | COMPLEXED TITANIUM (IV) COMPOUND AS REDUCING AGENT | THIOKOL CORPORATION (US) | 1979-11-06 | — | — | US | claimed |
| US-4002574-A | TITANIUM COMPOUNDS | VENTRON CORPORATION (US) | 1977-01-11 | — | — | US | claimed |