Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 9/20 | 0.65 |
| ▸ | CCNH | P51946 | 9/20 | 0.65 |
| ▸ | MNAT1 | P51948 | 7/20 | 0.65 |
| ▸ | CDK2 | P24941 | 14/20 | 0.52 |
| ▸ | CCNT1 | O60563 | 10/20 | 0.52 |
| ▸ | CCNK | O75909 | 10/20 | 0.52 |
| ▸ | CCNE1 | P24864 | 10/20 | 0.52 |
| ▸ | CDK9 | P50750 | 10/20 | 0.52 |
| ▸ | CDK12 | Q9NYV4 | 10/20 | 0.52 |
| ▸ | JUN | P05412 | 4/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25600689 | 1.00 | CDK7 (0.65) | CDK7CCNHMNAT1CDK2CCNT1 | |
| SCHEMBL25600682 | 1.00 | CDK7 (0.65) | CDK7CCNHMNAT1CDK2CCNT1 | |
| SCHEMBL25593182 | 0.87 | CDK2 (0.63) | CDK7CCNHMNAT1CDK2CCNT1 | |
| SCHEMBL30203953 | 0.86 | CDK2 (0.49) | CDK7CCNHMNAT1CDK2CCNT1 | |
| SCHEMBL25597589 | 0.84 | CCNK (0.65) | CDK7CCNHMNAT1CDK2CCNT1 | |
| SCHEMBL24588150 | 0.84 | CCNK (0.55) | CDK7CCNHMNAT1CDK2CCNT1 | |
| SCHEMBL30204470 | 0.82 | CDK2 (0.65) | CDK7CCNHMNAT1CDK2CCNT1 | |
| SCHEMBL25598690 | 0.82 | CDK2 (0.65) | CDK7CCNHMNAT1CDK2CCNT1 | |
| SCHEMBL30204055 | 0.82 | CCNK (0.69) | CDK7CCNHMNAT1CDK2CCNT1 | |
| SCHEMBL24588151 | 0.82 | CCNK (0.63) | CDK7CCNHMNAT1CDK2CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230062491-A1 | INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | MEDIC LIFE SCIENCES, INC. | 2023-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230062491-A1 | INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | CDK7, CDK3, CDK9 | CDK7 1/4885CCNH 33/4885MNAT1 92/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.