Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 7/20 | 0.42 |
| ▸ | CCNH | P51946 | 7/20 | 0.42 |
| ▸ | MNAT1 | P51948 | 7/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.42 |
| ▸ | CDK9 | P50750 | 5/20 | 0.42 |
| ▸ | MAPK3 | P27361 | 6/20 | 0.40 |
| ▸ | CCNK | O75909 | 8/20 | 0.39 |
| ▸ | CDK12 | Q9NYV4 | 7/20 | 0.39 |
| ▸ | CDK2 | P24941 | 6/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30203949 | 0.94 | CDK7 (0.42) | CDK7CCNHMNAT1CCNT1CDK9 | |
| SCHEMBL26967517 | 0.93 | CDK7 (0.43) | CDK7CCNHMNAT1CCNT1CDK9 | |
| SCHEMBL30204122 | 0.92 | CCNK (0.46) | CDK7CCNHMNAT1CCNT1CDK9 | |
| SCHEMBL30204488 | 0.91 | CCNK (0.41) | CDK7CCNHMNAT1CCNT1CDK9 | |
| SCHEMBL25268697 | 0.90 | CDK7 (0.43) | CDK7CCNHMNAT1CCNT1CDK9 | |
| SCHEMBL30439347 | 0.90 | CDK7 (0.43) | CDK7CCNHMNAT1CCNT1CDK9 | |
| SCHEMBL24087388 | 0.90 | CCNK (0.49) | CDK7CCNHMNAT1CCNT1CDK9 | |
| SCHEMBL29509168 | 0.90 | CCNK (0.49) | CDK7CCNHMNAT1CCNT1CDK9 | |
| SCHEMBL24087391 | 0.88 | CDK7 (0.40) | CDK7CCNHMNAT1CCNT1CDK9 | |
| SCHEMBL29509244 | 0.88 | CDK7 (0.40) | CDK7CCNHMNAT1CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240360165-A1 | INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | MEDIC LIFE SCIENCES, INC. | 2024-10-31 | — | — | US | disclosed |
| EP-3484871-B1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS INC (US) | 2023-06-07 | — | — | EP | disclosed |
| US-20230062491-A1 | INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | MEDIC LIFE SCIENCES, INC. | 2023-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240360165-A1 | INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | CDK7, CDK3, CDK9 | CDK7 1/4885CCNH 33/4885MNAT1 92/4885 |
| US-20230062491-A1 | INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | CDK7, CDK3, CDK9 | CDK7 1/4885CCNH 33/4885MNAT1 92/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.