Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2040732 | 1.00 | HCAR3 (0.49) | HCAR3KDM4EHPGDIP6K1FGFR1 | |
| SCHEMBL4181343 | 0.88 | KDM4E (0.57) | HCAR3KDM4EHPGDIP6K1FGFR1 | |
| SCHEMBL29606390 | 0.88 | KDM4E (0.57) | HCAR3KDM4EHPGDIP6K1FGFR1 | |
| SCHEMBL2040470 | 0.86 | KDM4E (0.46) | KDM4EHPGDIP6K1L3MBTL1ALDH1A1 | |
| SCHEMBL2611376 | 0.84 | HDAC6 (0.47) | KDM4EHPGDIP6K1L3MBTL1ALDH1A1 | |
| SCHEMBL9919053 | 0.80 | L3MBTL1 (0.41) | KDM4EHPGDIP6K1L3MBTL1ALDH1A1 | |
| SCHEMBL30186355 | 0.79 | ESR1 (0.62) | KDM4EHPGDIP6K1L3MBTL1ALDH1A1 | |
| SCHEMBL599310 | 0.79 | HCAR3 (0.65) | HCAR3HPGDFGFR1ALDH1A1LMNA | |
| SCHEMBL26783285 | 0.78 | JMJD6 (0.49) | KDM4EHPGDIP6K1L3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7330424 | 0.78 | HCAR3 (0.63) | HCAR3HPGDFGFR1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4337662-A1 | C-LINKED INHIBITORS OF ENL/AF9 YEATS | Bridge Medicines (US) | 2024-03-20 | — | — | EP | disclosed |
| WO-2022240830-A1 | C-LINKED INHIBITORS OF ENL/AF9 YEATS | BRIDGE MEDICINES (US) | 2022-11-17 | — | — | WO | disclosed |