Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | F2R | P25116 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30206507 | 0.80 | USP30 (0.33) | SCN4ASCN3A | |
| SCHEMBL30206374 | 0.78 | HSP90AA1 (0.37) | BCHESCN4ASCN3A | |
| SCHEMBL30206500 | 0.74 | TAAR1 (0.52) | NPC1RAB9AF2RSMN1; SMN2LMNA | |
| SCHEMBL6814101 | 0.64 | MEN1 (0.59) | NPC1RAB9AF2RSMN1; SMN2LMNA | |
| SCHEMBL7081264 | 0.64 | MEN1 (0.69) | NPC1RAB9ASMN1; SMN2LMNATP53 | |
| SCHEMBL4149607 | 0.63 | PIM1 (0.37) | BCHEL3MBTL1 | |
| SCHEMBL20864185 | 0.62 | FAAH (0.43) | BCHEL3MBTL1 | |
| SCHEMBL16060936 | 0.62 | PIM1 (0.36) | BCHEL3MBTL1 | |
| SCHEMBL27972423 | 0.62 | MEN1 (0.70) | NPC1RAB9AF2RSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL27667156 | 0.62 | RAB9A (0.48) | NPC1RAB9AF2RSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4392412-A1 | ABAD INHIBITOR COMPOUNDS | University Court of The University of St Andrews (GB) | 2024-07-03 | — | — | EP | disclosed |
| WO-2023026060-A1 | ABAD INHIBITOR COMPOUNDS | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2023-03-02 | — | — | WO | disclosed |