SCHEMBL4077735

SCHEMBL4077735

Cc1cc2cn[nH]c2c2c(=O)oc(-c3cc(C(F)F)nn3-c3ncccc3Cl)nc12

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ LIMK1 P53667 2/20 0.35
▸ LIMK2 P53671 2/20 0.35
▸ DHODH Q02127 1/20 0.32
▸ TRPV1 Q8NER1 3/20 0.32
▸ CYP17A1 P05093 1/20 0.32
▸ CYP1A2 P05177 1/20 0.32
▸ ELANE P08246 3/20 0.31
▸ ADORA2A P29274 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30206412 0.89 DHODH (0.31) DHODHTRPV1CYP17A1CYP1A2
SCHEMBL24947600 0.89 DHODH (0.31) DHODHTRPV1CYP17A1CYP1A2
SCHEMBL4073967 0.88 DHODH (0.42) DHODHTRPV1CYP17A1CYP1A2ELANE
SCHEMBL30206506 0.88 KDM4E (0.33) DHODHTRPV1CYP17A1CYP1A2ELANE
SCHEMBL24950042 0.88 KDM4E (0.33) DHODHTRPV1CYP17A1CYP1A2ELANE
SCHEMBL13749000 0.88 DHODH (0.32) DHODHTRPV1CYP17A1CYP1A2ELANE
SCHEMBL24950046 0.87 TRPV1 (0.33) LIMK1LIMK2DHODHTRPV1ELANE
SCHEMBL30206560 0.87 TRPV1 (0.33) LIMK1LIMK2DHODHTRPV1ELANE
SCHEMBL2591162 0.87 DHODH (0.34) DHODHTRPV1CYP17A1CYP1A2ELANE
SCHEMBL4074711 0.84 METAP2 (0.33) DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4376616-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR Syngenta Crop Protection AG (CH) 2024-06-05 — — EP disclosed
CN-117715523-A Methods for controlling diamide-resistant pests and compounds thereof 先正达农作物保护股份公司 2024-03-15 — — CN disclosed
WO-2023006634-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2023-02-02 — — WO disclosed
WO-2023006634-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2023-02-02 — — WO disclosed
WO-2014128136-A1 ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE (DE) 2014-08-28 — — WO disclosed
US-8658801-B2 Pesticides containing a bicyclic bisamide structure SYNGENTA CROP PROTECTION, LLC (US) 2014-02-25 — — US disclosed
US-8658801-B2 Pesticides containing a bicyclic bisamide structure SYNGENTA CROP PROTECTION, LLC (US) 2014-02-25 — — US disclosed
US-8658801-B2 Pesticides containing a bicyclic bisamide structure SYNGENTA CROP PROTECTION, LLC (US) 2014-02-25 — — US disclosed
US-20090298816-A1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE SYNGENTA CROP PROTECTION, INC. (US) 2009-12-03 — — US disclosed
US-20090298816-A1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE SYNGENTA CROP PROTECTION, INC. (US) 2009-12-03 — — US disclosed
US-20090298816-A1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE SYNGENTA CROP PROTECTION, INC. (US) 2009-12-03 — — US disclosed
EP-1984354-B1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE SYNGENTA PARTICIPATIONS AG (CH) 2009-08-05 — — EP disclosed
EP-1984354-A1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE Syngeta Participations AG (CH) 2008-10-29 — — EP disclosed
WO-2007093402-A1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE SYNGENTA PARTICIPATIONS AG (CH) 2007-08-23 — — WO disclosed
WO-2007093402-A1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE SYNGENTA PARTICIPATIONS AG (CH) 2007-08-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090298816-A1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE DDT, ACHE, GAP43 LIMK1 2859/4885LIMK2 3662/4885DHODH 786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback