Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18038967 | 1.00 | GAA (0.47) | GAACYP1A2CYP2D6PKMCYP2C19 | |
| SCHEMBL18038998 | 0.99 | GAA (0.46) | GAACYP1A2CYP2D6PKMCYP2C19 | |
| SCHEMBL18038984 | 0.92 | HTT (0.48) | GAACYP1A2CYP2D6PKMCYP2C19 | |
| SCHEMBL18038966 | 0.90 | HTT (0.52) | GAACYP1A2CYP2D6PKMCYP2C19 | |
| SCHEMBL18038982 | 0.89 | HTT (0.52) | GAACYP1A2CYP2D6PKMCYP2C19 | |
| SCHEMBL22050495 | 0.89 | GAA (0.44) | GAACYP1A2CYP2D6PKMCYP2C19 | |
| SCHEMBL21749683 | 0.89 | GAA (0.46) | GAACYP1A2CYP2D6PKMCYP2C19 | |
| SCHEMBL22051931 | 0.89 | GAA (0.42) | GAACYP1A2CYP2D6PKMCYP2C19 | |
| SCHEMBL18038965 | 0.88 | L3MBTL1 (0.52) | GAACYP1A2CYP2D6PKMCYP2C19 | |
| SCHEMBL22050826 | 0.88 | GAA (0.45) | GAACYP1A2CYP2D6PKMCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117295522-A | Compositions and methods for megalin inhibitors and photodynamic therapy for the treatment of cancer | 香港大学 | 2023-12-26 | — | — | CN | claimed |
| WO-2022237864-A1 | COMPOSITIONS AND METHODS OF MACROPINOCYTOSIS INHIBITORS AND PHOTODYNAMIC THERAPY TO TREAT CANCERS | THE UNIVERSITY OF HONG KONG (CN) | 2022-11-17 | — | — | WO | claimed |
| CN-119112874-A | Application of lupin alkane derivative in preparation of medicine for preventing and/or treating drug induced deafness | 吉林农业大学 | 2024-12-13 | — | — | CN | disclosed |
| CN-117295522-A | Compositions and methods for megalin inhibitors and photodynamic therapy for the treatment of cancer | 香港大学 | 2023-12-26 | — | — | CN | disclosed |
| WO-2022237864-A1 | COMPOSITIONS AND METHODS OF MACROPINOCYTOSIS INHIBITORS AND PHOTODYNAMIC THERAPY TO TREAT CANCERS | THE UNIVERSITY OF HONG KONG (CN) | 2022-11-17 | — | — | WO | disclosed |