Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | LPL | P06858 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23797605 | 1.00 | CSF1R (0.36) | CSF1RERN1CA1CA2CA9 | |
| SCHEMBL19869869 | 0.90 | ERN1 (0.40) | CSF1RERN1CA1CA2CA9 | |
| SCHEMBL29983777 | 0.87 | CSF1R (0.39) | CSF1RERN1CA1CA2CA9 | |
| SCHEMBL28591690 | 0.86 | CA1 (0.38) | CA1CA2CA9AAK1CA12 | |
| SCHEMBL22659553 | 0.83 | LPL (0.36) | CSF1RERN1CA1CA2CA9 | |
| SCHEMBL21225346 | 0.81 | CSF1R (0.35) | CSF1RERN1CA1CA2CA9 | |
| SCHEMBL16655541 | 0.80 | CSF1R (0.37) | CSF1RCA1CA2CA9AAK1 | |
| SCHEMBL30124524 | 0.78 | GAA (0.36) | CSF1RCA1CA2CA9AAK1 | |
| SCHEMBL529553 | 0.78 | MEN1 (0.39) | CSF1RERN1AAK1KMT2AEGFR | |
| SCHEMBL30038611 | 0.78 | CSF1R (0.38) | CSF1RCA1CA2CA9AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4114392-A1 | COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 | C4 Therapeutics, Inc. (US) | 2023-01-11 | — | — | EP | disclosed |