Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.66 |
| ▸ | HTR2A | P28223 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | HTR1D | P28221 | 1/20 | 0.51 |
| ▸ | HTR1B | P28222 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8747066 | 1.00 | TAAR1 (0.66) | TAAR1ADRA1AHTR2ACYP1A2HTR1A | |
| SCHEMBL12523559 | 0.89 | TAAR1 (0.53) | TAAR1ADRA1AHTR2ACYP1A2HTR1A | |
| SCHEMBL30557833 | 0.85 | TAAR1 (0.61) | TAAR1ADRA1AHTR2ACYP1A2HTR1A | |
| SCHEMBL10506599 | 0.85 | TAAR1 (0.61) | TAAR1ADRA1AHTR2ACYP1A2HTR1A | |
| SCHEMBL772819 | 0.85 | ADRA1A (0.50) | TAAR1ADRA1AHTR2AHTR1AMAOB | |
| SCHEMBL24252802 | 0.81 | CYP2D6 (0.51) | TAAR1ADRA1AHTR2AHTR1ASLC6A4 | |
| SCHEMBL30452001 | 0.81 | CYP2D6 (0.51) | TAAR1ADRA1AHTR2AHTR1ASLC6A4 | |
| SCHEMBL27955325 | 0.81 | SLC6A4 (0.44) | TAAR1ADRA1AHTR2AHTR1AMAPT | |
| SCHEMBL6451017 | 0.81 | HTR2A (0.67) | TAAR1ADRA1AHTR2ACYP1A2SLC6A4 | |
| SCHEMBL19003636 | 0.80 | ERBB2 (0.44) | TAAR1ADRA1AHTR2AHTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119569706-A | Therapeutic compounds | 希四克斯探索有限公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-112996785-B | Therapeutic compounds | 希四克斯探索有限公司 | 2024-12-06 | — | — | CN | disclosed |
| CN-109890797-B | Substituted carbon nucleoside derivatives useful as anticancer agents | 辉瑞公司 | 2023-02-28 | — | — | CN | disclosed |