Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252802 | 1.00 | CYP2D6 (0.51) | CYP2D6SLC6A4HTR2AKCNH2KDM4E | |
| SCHEMBL474014 | 0.85 | CYP2D6 (0.51) | CYP2D6SLC6A4HTR2AKCNH2KDM4E | |
| SCHEMBL7669104 | 0.85 | ALDH1A1 (0.54) | SLC6A4HTR2AKCNH2KDM4EALDH1A1 | |
| SCHEMBL27955325 | 0.81 | SLC6A4 (0.44) | SLC6A4HTR2AKCNH2ALDH1A1ADRA1A | |
| SCHEMBL8747066 | 0.81 | TAAR1 (0.66) | SLC6A4HTR2AKCNH2ADRA1ATAAR1 | |
| SCHEMBL30207828 | 0.81 | TAAR1 (0.66) | SLC6A4HTR2AKCNH2ADRA1ATAAR1 | |
| SCHEMBL19003636 | 0.80 | ERBB2 (0.44) | SLC6A4HTR2AKCNH2ADRA1ATAAR1 | |
| SCHEMBL19295490 | 0.80 | SLC6A4 (0.43) | SLC6A4HTR2AKCNH2ALDH1A1ADRA1A | |
| SCHEMBL10814111 | 0.80 | CYP2D6 (0.50) | CYP2D6KDM4EALDH1A1ADRA1ATAAR1 | |
| SCHEMBL5428835 | 0.80 | POLB (0.65) | KDM4EALDH1A1TDP1HSD17B10CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947903-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116261564-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-06-13 | — | — | CN | disclosed |
| EP-4185592-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | Annexon, Inc. (US) | 2023-05-31 | — | — | EP | disclosed |