Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PNP | P00491 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30208596 | 0.98 | POLA1 (0.54) | POLA1KDM4EPNPLMNATP53 | |
| SCHEMBL30208535 | 0.86 | HPGD (0.54) | TAS1R3TAS1R1 | |
| SCHEMBL30208557 | 0.84 | POLA1 (0.52) | POLA1KDM4EPNPLMNATP53 | |
| SCHEMBL30208450 | 0.84 | HPGD (0.54) | TAS1R3TAS1R1 | |
| SCHEMBL3625870 | 0.84 | POLA1 (0.63) | POLA1KDM4EPNPLMNATP53 | |
| SCHEMBL3625876 | 0.84 | POLA1 (0.63) | POLA1KDM4EPNPLMNATP53 | |
| SCHEMBL29559302 | 0.81 | POLA1 (0.66) | POLA1KDM4EPNPLMNATP53 | |
| SCHEMBL890293 | 0.81 | POLA1 (0.66) | POLA1KDM4EPNPLMNATP53 | |
| SCHEMBL30208550 | 0.81 | SLC29A1 (0.51) | — | |
| SCHEMBL16206605 | 0.81 | POLA1 (0.59) | POLA1KDM4EPNPLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001982-A1 | MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION | UNIVERSITÄT BASEL (CH) | 2023-01-26 | — | — | WO | claimed |