Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | BUB1 | O43683 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.31 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12153517 | 0.80 | HSD17B10 (0.44) | CTSDADRA2AADRA2BADRA2CKCNH3 | |
| SCHEMBL15704500 | 0.77 | RAPGEF4 (0.35) | — | |
| SCHEMBL30210189 | 0.76 | HDAC3 (0.43) | KCNH2 | |
| SCHEMBL28243194 | 0.75 | MKNK1 (0.38) | — | |
| SCHEMBL19529079 | 0.74 | — | — | |
| SCHEMBL20403503 | 0.74 | EPHX2 (0.38) | SLC6A2 | |
| SCHEMBL20147216 | 0.74 | PTGS1 (0.35) | — | |
| SCHEMBL13972894 | 0.73 | ALDH1A1 (0.39) | — | |
| SCHEMBL22651909 | 0.73 | MAPT (0.55) | SLC6A2 | |
| SCHEMBL13103263 | 0.73 | PTGIR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996939-A | AKT3 modulators | 乔治穆内有限责任公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-115867562-A | AKT3 modulators | 乔治穆内有限责任公司 | 2023-03-28 | — | — | CN | disclosed |