Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | TP53 | P04637 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | METAP2 | P50579 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 4/20 | 0.45 |
| ▸ | CCR1 | P32246 | 3/20 | 0.45 |
| ▸ | CCR5 | P51681 | 3/20 | 0.45 |
| ▸ | CCR8 | P51685 | 3/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30368831 | 0.85 | ACHE (0.64) | KDM4ELMNANPSR1ACHEMETAP1 | |
| SCHEMBL2712210 | 0.85 | ACHE (0.64) | KDM4ELMNANPSR1ACHEMETAP1 | |
| SCHEMBL4824379 | 0.80 | ACHE (0.71) | KDM4ESMN1; SMN2LMNANPC1PKM | |
| SCHEMBL4244311 | 0.80 | KDM4E (0.47) | KDM4ETP53SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL20652904 | 0.78 | KDM4E (0.56) | KDM4ETP53SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL4251618 | 0.77 | ACHE (0.45) | KDM4ETP53SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL29041842 | 0.77 | ADORA2A (0.52) | KDM4ETP53SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL5048878 | 0.74 | ACHE (0.53) | KDM4ELMNANPC1RAB9AMAPT | |
| SCHEMBL4251042 | 0.74 | CCR1 (0.47) | KDM4ETP53SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL4825118 | 0.74 | HSP90AA1 (0.50) | KDM4ETP53SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996939-A | AKT3 modulators | 乔治穆内有限责任公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-115867562-A | AKT3 modulators | 乔治穆内有限责任公司 | 2023-03-28 | — | — | CN | disclosed |