Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.49 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | TK1 | P04183 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15869137 | 0.98 | LMNA (0.53) | LMNASOAT2SOAT1TDP1EPHX2 | |
| SCHEMBL28583486 | 0.95 | LMNA (0.56) | LMNASOAT2SOAT1TDP1TK1 | |
| SCHEMBL18412481 | 0.95 | LMNA (0.56) | LMNASOAT2SOAT1TDP1TK1 | |
| SCHEMBL7054602 | 0.92 | LMNA (0.50) | LMNATDP1MAPTPPARGFFAR1 | |
| SCHEMBL11606804 | 0.91 | SOAT2 (0.51) | LMNASOAT2SOAT1TDP1EPHX2 | |
| SCHEMBL11606812 | 0.91 | SOAT2 (0.51) | LMNASOAT2SOAT1TDP1EPHX2 | |
| SCHEMBL11606807 | 0.91 | SOAT2 (0.51) | LMNASOAT2SOAT1TDP1EPHX2 | |
| SCHEMBL28997026 | 0.90 | LMNA (0.50) | LMNASOAT2SOAT1TDP1EPHX2 | |
| SCHEMBL29080210 | 0.89 | LMNA (0.59) | LMNATDP1TK1MEN1ALDH1A1 | |
| SCHEMBL29080212 | 0.89 | LMNA (0.59) | LMNATDP1TK1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4118090-A1 | METHODS OF MODULATING GASTROINTESTINAL MICROBIAL METABOLIC PATHWAYS AND METABOLITES | DSM IP Assets B.V. (NL) | 2023-01-18 | — | — | EP | disclosed |