Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 8/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 4/20 | 0.33 |
| ▸ | PARP1 | P09874 | 4/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.33 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.33 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.33 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.33 |
| ▸ | TAF1 | P21675 | 1/20 | 0.33 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2054595 | 0.83 | NOTUM (0.42) | NOTUMBTKFKBP5HDAC6NSD2 | |
| SCHEMBL24849937 | 0.76 | NPC1 (0.46) | NOTUMBTKFKBP5HDAC6NSD2 | |
| SCHEMBL24943297 | 0.76 | NOTUM (0.37) | NOTUMBTKFKBP5HDAC6NSD2 | |
| SCHEMBL1931574 | 0.74 | HSD17B10 (0.52) | NOTUMPARP1HDAC6 | |
| SCHEMBL19646434 | 0.73 | NOTUM (0.35) | NOTUMBTKNSD2ABL1PPARG | |
| SCHEMBL7241989 | 0.71 | NOTUM (0.34) | NOTUMBTKNSD2ABL1PPARG | |
| SCHEMBL7661963 | 0.70 | GRM8 (0.33) | NOTUMBTK | |
| SCHEMBL9301298 | 0.70 | NOTUM (0.33) | NOTUMNSD2ABL1PPARGRIN1 | |
| SCHEMBL5352433 | 0.69 | GAA (0.33) | NOTUMGPR84 | |
| SCHEMBL24880084 | 0.68 | ALDH1A1 (0.41) | BRD9TNKSPARP1TNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4139293-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2023-03-01 | — | — | EP | disclosed |