Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | BCR | P11274 | 2/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | STAMBP | O95630 | 1/20 | 0.33 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.33 |
| ▸ | MAP2 | P11137 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30007376 | 0.81 | TSHR (0.45) | CYP2C9CYP3A4 | |
| SCHEMBL25230064 | 0.73 | DYRK1A (0.32) | — | |
| SCHEMBL4589561 | 0.72 | TSHR (0.44) | ALPLSLC6A2SLC6A4SCN9ACYP2C9 | |
| SCHEMBL3784022 | 0.68 | SLC6A2 (0.46) | ALPLSLC6A2SLC6A4SCN9AABL1 | |
| SCHEMBL3641624 | 0.68 | APP (0.50) | SLC6A2SLC6A4 | |
| SCHEMBL12970641 | 0.68 | SLC6A2 (0.46) | ALPLSLC6A2SLC6A4ABL1BCR | |
| SCHEMBL30540337 | 0.68 | SLC6A2 (0.46) | ALPLSLC6A2SLC6A4SCN9ACHEK2 | |
| SCHEMBL14949401 | 0.67 | EPHX1 (0.45) | ALPLSLC6A2SLC6A4MAP2 | |
| SCHEMBL13733032 | 0.67 | SLC6A2 (0.45) | ALPLSLC6A2SLC6A4ABL1BCR | |
| SCHEMBL23081287 | 0.67 | PARP1 (0.45) | ALPLSLC6A2SLC6A4ABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4139293-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2023-03-01 | — | — | EP | disclosed |