Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 2/20 | 0.40 |
| ▸ | BPTF | Q12830 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23904826 | 0.85 | CYP3A4 (0.48) | HTTCYP3A4L3MBTL1HPGDSCA1 | |
| SCHEMBL30211319 | 0.81 | ALPL (0.35) | CYP3A4CYP2C9 | |
| SCHEMBL30211275 | 0.81 | MAPT (0.53) | HTTMKNK1MKNK2MAPK1L3MBTL1 | |
| SCHEMBL30007169 | 0.79 | TSHR (0.45) | TSHRAPOBEC3AHTTAPOBEC3GMKNK1 | |
| SCHEMBL23904829 | 0.76 | ACHE (0.41) | HTTALDH1A1PKMPOLB | |
| SCHEMBL30471201 | 0.74 | TSHR (0.41) | TSHRAPOBEC3AHTTAPOBEC3GMKNK1 | |
| SCHEMBL30211268 | 0.74 | TSHR (0.41) | TSHRAPOBEC3AHTTAPOBEC3GMKNK1 | |
| SCHEMBL30569750 | 0.74 | NQO2 (0.49) | ALDH1A1 | |
| SCHEMBL30007781 | 0.74 | TSHR (0.43) | TSHRAPOBEC3AHTTAPOBEC3GMKNK1 | |
| SCHEMBL30471318 | 0.73 | TSHR (0.40) | TSHRAPOBEC3AHTTAPOBEC3GMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4139293-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2023-03-01 | — | — | EP | disclosed |
| CN-115461336-A | RSV inhibiting 3-substituted quinoline and cinnoline derivatives | 爱尔兰詹森科学公司 | 2022-12-09 | — | — | CN | disclosed |