Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10744650 | 1.00 | SIGMAR1 (0.49) | SIGMAR1DRD2HTR2ATRPM8ADRA1D | |
| SCHEMBL3926924 | 0.78 | SIGMAR1 (0.47) | SIGMAR1DRD2HTR2ATRPM8ADRA1D | |
| SCHEMBL3433240 | 0.77 | SIGMAR1 (0.48) | SIGMAR1DRD2HTR2ATRPM8ADRA1D | |
| SCHEMBL28685780 | 0.76 | SIGMAR1 (0.43) | SIGMAR1DRD2HTR2ATRPM8ADRA1D | |
| SCHEMBL3560241 | 0.75 | SIGMAR1 (0.57) | SIGMAR1DRD2HTR2ATRPM8ADRA1D | |
| SCHEMBL462820 | 0.75 | SIGMAR1 (0.45) | SIGMAR1DRD2HTR2ATRPM8ADRA1D | |
| SCHEMBL29392702 | 0.75 | SIGMAR1 (0.45) | SIGMAR1DRD2HTR2ATRPM8ADRA1D | |
| SCHEMBL3113866 | 0.75 | SIGMAR1 (0.45) | SIGMAR1DRD2HTR2ATRPM8ADRA1D | |
| SCHEMBL6467973 | 0.75 | SIGMAR1 (0.45) | SIGMAR1DRD2HTR2ATRPM8ADRA1D | |
| SCHEMBL30376964 | 0.75 | SIGMAR1 (0.57) | SIGMAR1DRD2HTR2ATRPM8ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11505545-B2 | Anthelmintic quinoline-3-carboxamide derivatives | BAYER ANIMAL HEALTH GMBH (DE) | 2022-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11505545-B2 | Anthelmintic quinoline-3-carboxamide derivatives | HRH4, HRH2, H1-5 | SIGMAR1 1105/4885DRD2 1573/4885HTR2A 1215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.