SCHEMBL3433240

SCHEMBL3433240

ClC1(c2ccccc2)CCc2ccccc2O1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.48
DRD2 P14416 2/20 0.42
HTR2A P28223 2/20 0.42
TRPM8 Q7Z2W7 2/20 0.40
TSHR P16473 1/20 0.37
HDAC9 Q9UKV0 1/20 0.36
ADRA1D P25100 1/20 0.35
ADRA1A P35348 1/20 0.35
ADRA1B P35368 1/20 0.35
EPHX2 P34913 2/20 0.34
EPHX1 P07099 1/20 0.34
HTR2C P28335 1/20 0.33
KCNH2 Q12809 1/20 0.33
MEN1 O00255 1/20 0.32
CYP2C9 P11712 1/20 0.32
KMT2A Q03164 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11224754 0.81 SIGMAR1 (0.37) SIGMAR1HDAC9MEN1CYP2C9KMT2A
SCHEMBL2009422 0.78 SIGMAR1 (0.41) SIGMAR1DRD2HTR2ATRPM8ADRA1D
SCHEMBL9113086 0.78 SIGMAR1 (0.46) SIGMAR1DRD2HTR2ATRPM8TSHR
SCHEMBL10744650 0.77 SIGMAR1 (0.49) SIGMAR1DRD2HTR2ATRPM8TSHR
SCHEMBL30211327 0.77 SIGMAR1 (0.49) SIGMAR1DRD2HTR2ATRPM8TSHR
SCHEMBL11228399 0.75 SIGMAR1 (0.44) SIGMAR1DRD2HTR2ATRPM8HDAC9
SCHEMBL11220183 0.75 HSD11B1 (0.46) SIGMAR1DRD2HTR2ATRPM8ADRA1D
SCHEMBL1246125 0.75 SIGMAR1 (0.44) SIGMAR1DRD2HTR2ATRPM8HDAC9
SCHEMBL30637538 0.75 SIGMAR1 (0.44) SIGMAR1DRD2HTR2ATRPM8TSHR
SCHEMBL11395060 0.75 SIGMAR1 (0.44) SIGMAR1DRD2HTR2ATRPM8HDAC9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11529302-B2 Composition, artificial nail composition, nail decoration material, artificial nail, stored container, image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2022-12-20 US disclosed
US-20200038309-A1 COMPOSITION, ARTIFICIAL NAIL COMPOSITION, NAIL DECORATION MATERIAL, ARTIFICIAL NAIL, STORED CONTAINER, IMAGE FORMING APPARATUS, AND IMAGE FORMING METHOD RICOH COMPANY, LTD. (JP) 2020-02-06 US disclosed
US-20200038310-A1 COMPOSITION, ARTIFICIAL NAIL COMPOSITION, NAIL DECORATION MATERIAL, ARTIFICIAL NAIL, STORED CONTAINER, IMAGE FORMING APPARATUS, AND IMAGE FORMING METHOD RICOH COMPANY, LTD. (JP) 2020-02-06 US disclosed
EP-2705953-B1 Ink pack FUJIFILM CORP (JP) 2018-01-03 EP disclosed
EP-2573146-B1 INK COMPOSITION FOR INK JET RECORDING, INK PACK, AND INK JET RECORDING METHOD FUJIFILM CORP (JP) 2016-11-30 EP disclosed
EP-2832805-B1 INKJET INK COMPOSITION, INKJET RECORDING METHOD, AND PRINTED MATTER FUJIFILM CORP (JP) 2016-09-07 EP disclosed
US-9290015-B2 Inkjet recording method and printed material FUJIFILM CORPORATION (JP) 2016-03-22 US disclosed
US-8991994-B2 Ink pack FUJIFILM CORPORATION (JP) 2015-03-31 US disclosed
EP-2700509-B1 Inkjet recording method FUJIFILM CORP (JP) 2015-03-04 EP disclosed
EP-2832805-A1 INKJET INK COMPOSITION, INKJET RECORDING METHOD, AND PRINTED MATTER FUJIFILM Corporation (JP) 2015-02-04 EP disclosed
EP-2832553-A1 INKJET RECORDING METHOD AND PRINTED MATTER FUJIFILM Corporation (JP) 2015-02-04 EP disclosed
EP-2705953-A1 Ink pack Fujifilm Corporation (JP) 2014-03-12 EP disclosed
US-20140063149-A1 INK PACK FUJIFILM CORPORATION (JP) 2014-03-06 US disclosed
US-20140055539-A1 INKJET RECORDING METHOD AND PRINTED MATERIAL FUJIFILM CORPORATION (JP) 2014-02-27 US disclosed
EP-2700509-A1 Inkjet recording method and printed material Fujifilm Corporation (JP) 2014-02-26 EP disclosed
US-8415409-B2 Radiation-curable ink composition for inkjet recording, inkjet recording method, and printed matter FUJIFILM CORPORATION (JP) 2013-04-09 US disclosed
EP-2573146-A1 Ink composition for ink jet recording, ink pack, and ink jet recording method Fujifilm Corporation (JP) 2013-03-27 EP disclosed
EP-2223977-B1 Radiation-curable ink composition for inkjet recording, inkjet recording method, and printed matter FUJIFILM CORP (JP) 2013-03-13 EP disclosed
US-20100221506-A1 RADIATION-CURABLE INK COMPOSITION FOR INKJET RECORDING,INKJET RECORDING METHOD, AND PRINTED MATTER FUJIFILM CORPORATION (JP) 2010-09-02 US disclosed
EP-2223977-A1 Radiation-curable ink composition for inkjet recording, inkjet recording method, and printed matter FUJIFILM Corporation (JP) 2010-09-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200038309-A1 COMPOSITION, ARTIFICIAL NAIL COMPOSITION, NAIL DECORATION MATERIAL, ARTIFICIAL NAIL, STORED CONTAINER, IMAGE FORMING APPARATUS, AND IMAGE FORMING METHOD NACA, PIK3C3, DPM1 SIGMAR1 430/4885DRD2 977/4885HTR2A 3223/4885
US-20200038310-A1 COMPOSITION, ARTIFICIAL NAIL COMPOSITION, NAIL DECORATION MATERIAL, ARTIFICIAL NAIL, STORED CONTAINER, IMAGE FORMING APPARATUS, AND IMAGE FORMING METHOD NACA, PIK3C3, ACR SIGMAR1 193/4885DRD2 893/4885HTR2A 2521/4885
US-11529302-B2 Composition, artificial nail composition, nail decoration material, artificial nail, stored container, image forming apparatus, and image forming method NACA, PIK3C3, ACR SIGMAR1 193/4885DRD2 893/4885HTR2A 2521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.