SCHEMBL30211772

SCHEMBL30211772

O=C(Nc1ccccc1-c1nc2ccccc2s1)c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 7/20 0.64
MAPK1 P28482 2/20 0.64
USP2 O75604 1/20 0.64
TSHR P16473 1/20 0.64
ATM Q13315 1/20 0.64
HSD17B10 Q99714 1/20 0.64
TDP1 Q9NUW8 1/20 0.64
HPGD P15428 3/20 0.63
MAPT P10636 9/20 0.62
THRB P10828 1/20 0.62
RXFP1 Q9HBX9 2/20 0.61
ALDH1A1 P00352 2/20 0.60
POLB P06746 2/20 0.59
LMNA P02545 5/20 0.57
KDM4E B2RXH2 1/20 0.55
HTT P42858 1/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
NPSR1 Q6W5P4 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25916299 1.00 TP53 (0.64) TP53MAPK1USP2TSHRATM
SCHEMBL25916389 0.89 MAPT (0.53) TP53MAPK1USP2TSHRATM
SCHEMBL25916406 0.87 MAPT (0.58) TP53MAPK1USP2TSHRATM
SCHEMBL25916397 0.86 MAPT (0.67) TP53MAPK1USP2TSHRATM
SCHEMBL25916301 0.85 MAPT (0.52) TP53MAPK1USP2TSHRATM
SCHEMBL30362576 0.85 MAPT (0.52) TP53MAPK1USP2TSHRATM
SCHEMBL12963284 0.84 MAPT (0.71) TP53MAPK1USP2TSHRATM
SCHEMBL12963238 0.84 THRB (0.73) TP53MAPK1USP2TSHRATM
SCHEMBL30362646 0.83 HPGD (0.78) TP53MAPK1USP2TSHRATM
SCHEMBL25916294 0.83 HPGD (0.78) TP53MAPK1USP2TSHRATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4164891-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS Crime Science Technology (FR) 2023-04-19 EP claimed
EP-4164891-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS Crime Science Technology (FR) 2023-04-19 EP disclosed
CN-115768631-A Fluorescent composition comprising at least one benzoxazole compound for protecting products 犯罪科学技术公司 2023-03-07 CN disclosed