SCHEMBL25916406

SCHEMBL25916406

O=C(Nc1cc(Cl)ccc1-c1nc2ccccc2s1)c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.58
NPSR1 Q6W5P4 1/20 0.58
HPGD P15428 3/20 0.53
ALDH1A1 P00352 1/20 0.53
LMNA P02545 1/20 0.51
TP53 P04637 5/20 0.50
USP2 O75604 1/20 0.50
TSHR P16473 1/20 0.50
MAPK1 P28482 1/20 0.50
ATM Q13315 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
THRB P10828 3/20 0.49
RXFP1 Q9HBX9 1/20 0.48
DHODH Q02127 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30362569 0.88 MAPT (0.49) MAPTNPSR1HPGDALDH1A1LMNA
SCHEMBL25916355 0.88 MAPT (0.49) MAPTNPSR1HPGDALDH1A1LMNA
SCHEMBL30211772 0.87 TP53 (0.64) MAPTNPSR1HPGDALDH1A1LMNA
SCHEMBL25916299 0.87 TP53 (0.64) MAPTNPSR1HPGDALDH1A1LMNA
SCHEMBL25916343 0.86 MAPT (0.47) MAPTNPSR1HPGDALDH1A1LMNA
SCHEMBL30362726 0.86 MAPT (0.47) MAPTNPSR1HPGDALDH1A1LMNA
SCHEMBL25916362 0.85 MAPT (0.61) MAPTNPSR1HPGDALDH1A1LMNA
SCHEMBL30362693 0.85 MAPT (0.61) MAPTNPSR1HPGDALDH1A1LMNA
SCHEMBL30362639 0.82 MAPT (0.55) MAPTNPSR1HPGDALDH1A1TP53
SCHEMBL25916341 0.82 MAPT (0.55) MAPTNPSR1HPGDALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230235190-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS Crime Science Technology (FR) 2023-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230235190-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS TUBB3, TUBA3C, PHB1 MAPT 318/4885NPSR1 4524/4885HPGD 1287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.