SCHEMBL30212182

SCHEMBL30212182

CCSc1cccc2c1c(=O)c(C(=O)O)nn2-c1ccc(OC(F)(F)F)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TEAD1 P28347 1/20 0.42
▸ TEAD4 Q15561 1/20 0.42
▸ TEAD2 Q15562 1/20 0.42
▸ TEAD3 Q99594 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ TP53 P04637 3/20 0.38
▸ MAPT P10636 1/20 0.38
▸ ABCB1 P08183 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ PTGER4 P35408 1/20 0.37
▸ SLC5A1 P13866 1/20 0.36
▸ SLC5A2 P31639 1/20 0.36
▸ MARS1 P56192 1/20 0.36
▸ ELANE P08246 1/20 0.36
▸ CNR1 P21554 1/20 0.36
▸ CNR2 P34972 1/20 0.36
▸ PPARD Q03181 1/20 0.36
▸ PPARA Q07869 1/20 0.36
▸ NR3C1 P04150 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24047679 1.00 TEAD1 (0.42) TEAD1TEAD4TEAD2TEAD3ALDH1A1
SCHEMBL24048261 0.91 SLC5A1 (0.45) TEAD1TEAD4TEAD2TEAD3ALDH1A1
SCHEMBL30212111 0.91 SLC5A1 (0.45) TEAD1TEAD4TEAD2TEAD3ALDH1A1
SCHEMBL30527202 0.90 TEAD1 (0.40) TEAD1TEAD4TEAD2TEAD3L3MBTL1
SCHEMBL24047181 0.90 TEAD1 (0.40) TEAD1TEAD4TEAD2TEAD3L3MBTL1
SCHEMBL24048177 0.89 TEAD1 (0.41) TEAD1TEAD4TEAD2TEAD3L3MBTL1
SCHEMBL30286784 0.89 TEAD1 (0.41) TEAD1TEAD4TEAD2TEAD3L3MBTL1
SCHEMBL30311004 0.84 TP53 (0.44) TEAD1TEAD4TEAD2TEAD3L3MBTL1
SCHEMBL26074779 0.84 TP53 (0.44) TEAD1TEAD4TEAD2TEAD3L3MBTL1
SCHEMBL24046609 0.84 MEN1 (0.38) TEAD1TEAD4TEAD2TEAD3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230250066-A1 HERBICIDAL CINNOLINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2023-08-10 — — US disclosed
EP-4153573-A1 HERBICIDAL CINNOLINE DERIVATIVES Syngenta Crop Protection AG (CH) 2023-03-29 — — EP disclosed
CN-115697975-A Herbicidal cinnoline derivatives 先正达农作物保护股份公司 2023-02-03 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230250066-A1 HERBICIDAL CINNOLINE DERIVATIVES DDT, CYP1B1, DERL1 TEAD1 3725/4885TEAD4 4220/4885TEAD2 4506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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