Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.37 |
| ▸ | TEAD4 | Q15561 | 2/20 | 0.37 |
| ▸ | TEAD2 | Q15562 | 2/20 | 0.37 |
| ▸ | TEAD3 | Q99594 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30212143 | 1.00 | MEN1 (0.38) | MEN1ALDH1A1KMT2ATEAD1TEAD4 | |
| SCHEMBL24047754 | 0.88 | ALDH1A1 (0.49) | MEN1ALDH1A1KMT2ATEAD1TEAD4 | |
| SCHEMBL30212196 | 0.88 | ALDH1A1 (0.49) | MEN1ALDH1A1KMT2ATEAD1TEAD4 | |
| SCHEMBL24048177 | 0.86 | TEAD1 (0.41) | TEAD1TEAD4TEAD2TEAD3PDE5A | |
| SCHEMBL30286784 | 0.86 | TEAD1 (0.41) | TEAD1TEAD4TEAD2TEAD3PDE5A | |
| SCHEMBL24047181 | 0.84 | TEAD1 (0.40) | TEAD1TEAD4TEAD2TEAD3CCNA2 | |
| SCHEMBL30212182 | 0.84 | TEAD1 (0.42) | ALDH1A1TEAD1TEAD4TEAD2TEAD3 | |
| SCHEMBL30527202 | 0.84 | TEAD1 (0.40) | TEAD1TEAD4TEAD2TEAD3CCNA2 | |
| SCHEMBL24047679 | 0.84 | TEAD1 (0.42) | ALDH1A1TEAD1TEAD4TEAD2TEAD3 | |
| SCHEMBL8830041 | 0.82 | RORC (0.45) | TEAD1TEAD4TEAD2TEAD3CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250066-A1 | HERBICIDAL CINNOLINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2023-08-10 | — | — | US | disclosed |
| US-20230250066-A1 | HERBICIDAL CINNOLINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2023-08-10 | — | — | US | disclosed |
| US-20230250066-A1 | HERBICIDAL CINNOLINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2023-08-10 | — | — | US | disclosed |
| CN-115697975-A | Herbicidal cinnoline derivatives | 先正达农作物保护股份公司 | 2023-02-03 | — | — | CN | disclosed |
| WO-2021233787-A1 | HERBICIDAL CINNOLINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2021-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250066-A1 | HERBICIDAL CINNOLINE DERIVATIVES | DDT, CYP1B1, DERL1 | MEN1 500/4885ALDH1A1 7/4885KMT2A 2250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.