Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30212781 | 1.00 | TSHR (0.38) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL30212851 | 1.00 | TSHR (0.38) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL30212644 | 1.00 | TSHR (0.38) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL30212768 | 1.00 | TSHR (0.38) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL30212634 | 1.00 | TSHR (0.38) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL30212794 | 1.00 | TSHR (0.38) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL9784569 | 0.98 | GNAI3 (0.37) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL30212979 | 0.98 | GNAI3 (0.37) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL30213165 | 0.98 | GNAI3 (0.37) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL30212762 | 0.98 | GNAI3 (0.37) | TSHRTHRBGNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023046704-A1 | ELECTROCHEMICAL GAS SENSOR AND ELECTROLYTE FOR AN ELECTROCHEMICAL GAS SENSOR | Dräger Safety AG & Co. KGaA (DE) | 2023-03-30 | — | — | WO | disclosed |
| EP-4155723-A1 | ELECTROCHEMICAL GAS SENSOR AND ELECTROLYTE FOR AN ELECTROCHEMICAL GAS SENSOR | Dräger Safety AG & Co. KGaA (DE) | 2023-03-29 | — | — | EP | disclosed |