Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL326784 | 1.00 | KCNH2 (0.50) | KCNH2HSD17B10HDAC8 | |
| SCHEMBL29726482 | 0.98 | KCNH2 (0.52) | KCNH2HSD17B10HDAC8 | |
| SCHEMBL2938596 | 0.98 | KCNH2 (0.52) | KCNH2HSD17B10HDAC8 | |
| Hydrochloric Acid SCHEMBL27658826 | 0.92 | KCNH2 (0.61) | KCNH2HSD17B10 | |
| Hydrochloric Acid SCHEMBL3028802 | 0.92 | KCNH2 (0.61) | KCNH2HSD17B10 | |
| Hydrochloric Acid SCHEMBL27658816 | 0.92 | KCNH2 (0.61) | KCNH2HSD17B10 | |
| Hydrochloric Acid SCHEMBL8508951 | 0.92 | KCNH2 (0.61) | KCNH2HSD17B10 | |
| SCHEMBL1817713 | 0.91 | KCNH2 (0.46) | KCNH2HSD17B10HDAC8 | |
| SCHEMBL28905757 | 0.90 | KCNH2 (0.63) | KCNH2HSD17B10 | |
| SCHEMBL5288629 | 0.90 | KCNH2 (0.63) | KCNH2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023046704-A1 | ELECTROCHEMICAL GAS SENSOR AND ELECTROLYTE FOR AN ELECTROCHEMICAL GAS SENSOR | Dräger Safety AG & Co. KGaA (DE) | 2023-03-30 | — | — | WO | disclosed |
| EP-4155723-A1 | ELECTROCHEMICAL GAS SENSOR AND ELECTROLYTE FOR AN ELECTROCHEMICAL GAS SENSOR | Dräger Safety AG & Co. KGaA (DE) | 2023-03-29 | — | — | EP | disclosed |