Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8508951 | 1.00 | KCNH2 (0.61) | KCNH2HSD17B10MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL27658826 | 1.00 | KCNH2 (0.61) | KCNH2HSD17B10MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL27658816 | 1.00 | KCNH2 (0.61) | KCNH2HSD17B10MEN1MAPTMAPK1 | |
| SCHEMBL28905757 | 0.98 | KCNH2 (0.63) | KCNH2HSD17B10LIPG | |
| SCHEMBL2563319 | 0.98 | KCNH2 (0.63) | KCNH2HSD17B10LIPG | |
| SCHEMBL27633428 | 0.98 | KCNH2 (0.63) | KCNH2HSD17B10LIPG | |
| SCHEMBL5288629 | 0.98 | KCNH2 (0.63) | KCNH2HSD17B10LIPG | |
| Bromide SCHEMBL27658806 | 0.96 | KCNH2 (0.61) | KCNH2HSD17B10KMT2ASMN1; SMN2LIPG | |
| Iodide SCHEMBL28049744 | 0.95 | KCNH2 (0.59) | KCNH2HSD17B10LIPG | |
| Iodide SCHEMBL28049741 | 0.93 | KCNH2 (0.58) | KCNH2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9631045-B2 | Polycarbodiimides having onium salt groups | PPG INDUSTRIES OHIO, INC. (US) | 2017-04-25 | — | — | US | disclosed |
| US-8981005-B2 | Coating compositions that include onium salt group containing polycarbodiimides | PPG INDUSTRIES OHIO, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| WO-2014099923-A1 | IMPROVED ANTIMICROBIAL EFFECTS IN POLYMERS | BASF SE (DE) | 2014-06-26 | — | — | WO | disclosed |
| US-20140170238-A1 | Antimicrobial effects in polymers | BASF SE (DE) | 2014-06-19 | — | — | US | disclosed |
| US-8258202-B2 | Antimicrobial coating compositions, related coatings and coated substrates | PPG INDUSTRIES OHIO, INC (US) | 2012-09-04 | — | — | US | disclosed |
| WO-2010093536-A1 | POLYCARBODIIMIDES HAVING ONIUM SALT GROUPS | PPG INDUSTRIES OHIO, INC. (US) | 2010-08-19 | — | — | WO | disclosed |
| US-20100204515-A1 | POLYCARBODIIMIDES HAVING ONIUM SALT GROUPS | PPG INDUSTRIES OHIO, INC. (US) | 2010-08-12 | — | — | US | disclosed |
| US-20100204414-A1 | COATING COMPOSITIONS THAT INCLUDE ONIUM SALT GROUP CONTAINING POLYCARBODIIMIDES | PPG INDUSTRIES OHIO, INC. (US) | 2010-08-12 | — | — | US | disclosed |
| US-20100204357-A1 | ANTIMICROBIAL COATING COMPOSITIONS, RELATED COATINGS AND COATED SUBSTRATES | PPG INDUSTRIES OHIO, INC. (US) | 2010-08-12 | — | — | US | disclosed |
| US-6855328-B2 | Antimicrobial and antiviral compositions containing an oxidizing species | ECOLAB INC. (US) | 2005-02-15 | — | — | US | disclosed |
| WO-2003105583-A2 | ANTIMICROBIAL AND ANTIVIRAL COMPOSITIONS CONTAINING AN OXIDIZING SPECIES | ECOLAB INC (US) | 2003-12-24 | — | — | WO | disclosed |
| US-20030185902-A1 | Antimicrobial and antiviral compositions containing an oxidizing species | ECOLAB INC. | 2003-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030185902-A1 | Antimicrobial and antiviral compositions containing an oxidizing species | LPO, IFNG, HAO2 | KCNH2 1157/4885HSD17B10 1068/4885MEN1 3775/4885 |
| US-20100204515-A1 | POLYCARBODIIMIDES HAVING ONIUM SALT GROUPS | CA7, HDAC6, HDAC10 | KCNH2 197/4885HSD17B10 1954/4885MEN1 1136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.