Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 5/20 | 0.44 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24028067 | 1.00 | METAP2 (0.47) | METAP2TSHRRECQLNPC1RAB9A | |
| SCHEMBL2658449 | 0.79 | IDO1 (0.47) | METAP2NPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL11730368 | 0.78 | KEAP1 (0.55) | METAP2TSHRNPC1RAB9AMEN1 | |
| SCHEMBL31402293 | 0.77 | DYRK1A (0.44) | ALDH1A1AXLDYRK3CCNT1CDK9 | |
| SCHEMBL29796022 | 0.75 | KEAP1 (0.61) | METAP2TSHRRECQLNPC1RAB9A | |
| SCHEMBL1532168 | 0.75 | KEAP1 (0.61) | METAP2TSHRRECQLNPC1RAB9A | |
| SCHEMBL3346256 | 0.72 | TSHR (0.49) | METAP2TSHRRECQLNPC1RAB9A | |
| SCHEMBL8402151 | 0.71 | CYP2A6 (0.53) | METAP2ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL24270330 | 0.71 | NPC1 (0.65) | METAP2TSHRRECQLNPC1RAB9A | |
| SCHEMBL30165348 | 0.71 | NPC1 (0.65) | METAP2TSHRRECQLNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118256096-A | High-permeability aging-resistant fog seal material and preparation method thereof | 太行城乡建设集团有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-118256096-A | High-permeability aging-resistant fog seal material and preparation method thereof | 太行城乡建设集团有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-118256096-A | High-permeability aging-resistant fog seal material and preparation method thereof | 太行城乡建设集团有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-115697974-A | Imidazole 3-oxide derivative based ACSS2 inhibitors and methods of use thereof | 美特波米德有限公司 | 2023-02-03 | — | — | CN | disclosed |